Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/12867
標題: 2009-2011年間台灣鸚鵡披衣菌之盛行率調查及鸚鵡披衣菌之主要外膜蛋白基因序列分析
The prevalence of Chlamydophila psittaci and Alignment Analysis of Major Outer Membrane Protein Gene in Taiwan between 2009 and 2011
作者: 劉思妤
Liu, Szu-Yu
關鍵字: Chlamydophila psittaci
鸚鵡披衣菌
waterfowl
paittacine bird
wild bird
水禽類
鸚鵡鳥類
野生鳥類
出版社: 獸醫學系暨研究所
引用: 方偉宏。台灣鳥類全圖鑑、自然珍藏系列28。貓頭鷹出版社。2008。 行政院衛生署疾病管制局、中華民國比較病理學會、台灣感染症醫學會、台灣醫院感染管制學會。人畜共通傳染病臨床指引。行政院衛生署疾病管制局。2009。135-137。 葉明穎。台灣地區鴿子披衣菌血清學調查及分離。國立台灣大學碩士論文。1997。 劉振軒、潘銘正、徐榮彬、蔡睦宗、林滄龍、張世忠、陳裕文、卓宜興、何勝裕。世界動物衛生組織及甲乙丙類通報動物傳染病 第二冊。國立臺灣大學獸醫專業學院。2008。78-84。 魯懿萍、賴以祥、廖明輝、黃旭田、洪信雄。鳥禽類披衣菌症快速診斷技術之開發與應用。中華民國獸醫學會暨台灣畜牧獸醫學會九十一年度聯合學術論文發表會。2002。110。 Andersen, A., Vanrompay, D. 2008. Avian chlamydiosis (Psittacosis, Ornithosis). In Diseases of poultry (Iowa state university Press, Ames, IA, USA), pp. 971-986. Andersen, A.A., 1991, Serotyping of Chlamydia psittaci isolates using serovar-specific monoclonal antibodies with the microimmunofluorescence test. J Clin Microbiol 29, 707-711. Andersen, A.A., 1996, Comparison of pharyngeal, fecal, and cloacal samples for the isolation of Chlamydia psittaci from experimentally infected cockatiels and turkeys. J Vet Diagn Invest 8, 448-450. Azuma, Y., Hirakawa, H., Yamashita, A., Cai, Y., Rahman, M.A., Suzuki, H., Mitaku, S., Toh, H., Goto, S., Murakami, T., Sugi, K., Hayashi, H., Fukushi, H., Hattori, M., Kuhara, S., Shirai, M., 2006, Genome sequence of the cat pathogen, Chlamydophila felis. DNA Res 13, 15-23. Baehr, W., Zhang, Y.X., Joseph, T., Su, H., Nano, F.E., Everett, K.D., Caldwell, H.D., 1988, Mapping antigenic domains expressed by Chlamydia trachomatis major outer membrane protein genes. Proc Natl Acad Sci U S A 85, 4000-4004. Beeckman, D.S., Geens, T., Timmermans, J.P., Van Oostveldt, P., Vanrompay, D.C., 2008, Identification and characterization of a type III secretion system in Chlamydophila psittaci. Vet Res 39, 27. Beeckman, D.S., Vanrompay, D.C., 2009, Zoonotic Chlamydophila psittaci infections from a clinical perspective. Clin Microbiol Infect 15, 11-17. Beeckman, D.S., Vanrompay, D.C., 2010, Biology and intracellular pathogenesis of high or low virulent Chlamydophila psittaci strains in chicken macrophages. Vet Microbiol 141, 342-353. Belchior, E., Barataud, D., Ollivier, R., Capek, I., Laroucau, K., De Barbeyrac, B., Hubert, B., 2011, Psittacosis outbreak after participation in a bird fair, Western France, December 2008. Epidemiol Infect 139, 1637-41. Bevan, B.J., Bracewell, C.D., 1986, Chlamydiosis in birds in Great Britain. 2. Isolations of Chlamydia psittaci from birds sampled between 1976 and 1984. The Journal of hygiene 96, 453-458. Branley, J.M., Roy, B., Dwyer, D.E., Sorrell, T.C., 2008, Real-time PCR detection and quantitation of Chlamydophila psittaci in human and avian specimens from a veterinary clinic cluster. Eur J Clin Microbiol Infect Dis 27, 269-273. Bush, R.M., Everett, K.D., 2001, Molecular evolution of the Chlamydiaceae. Int J Syst Evol Microbiol 51, 203-220. Celebi, B.S., Ak, S., 2006, A comparative study of detecting Chlamydophila psittaci in pet birds using isolation in embryonated egg and polymerase chain reaction. Avian Dis 50, 489-493. Circella, E., Pugliese, N., Todisco, G., Cafiero, M.A., Sparagano, O.A., Camarda, A., 2011, Chlamydia psittaci infection in canaries heavily infested by Dermanyssus gallinae. Exp Appl Acarol 55, 329-338. de Freitas Raso, T., Seixas, G.H., Guedes, N.M., Pinto, A.A., 2006, Chlamydophila psittaci in free-living Blue-fronted Amazon parrots (Amazona aestiva) and Hyacinth macaws (Anodorhynchus hyacinthinus) in the Pantanal of Mato Grosso do Sul, Brazil. Vet Microbiol 117, 235-241. Dean, D., Kandel, R.P., Adhikari, H.K., Hessel, T., 2008, Multiple Chlamydiaceae species in trachoma: implications for disease pathogenesis and control. PLoS Med 5, e14. Denamur, E., Sayada, C., Souriau, A., Orfila, J., Rodolakis, A., Elion, J., 1991, Restriction pattern of the major outer-membrane protein gene provides evidence for a homogeneous invasive group among ruminant isolates of Chlamydia psittaci. J Gen Microbiol 137, 2525-2530. Di Francesco, A., Donati, M., Carelle, M.S., Cevenini, R., Baldelli, R., 2004, Molecular characterisation of a Chlamydophila felis isolate from a cat in Italy. Vet Rec 154, 239-240. Dickx, V., Beeckman, D.S.A., Dossche, L., Tavernier, P., Vanrompay, D., 2010a, Chlamydophila psittaci in homing and feral pigeons and zoonotic transmission. J Med Microbiol 59, 1348-1353. Dickx, V., Geens, T., Deschuyffeleer, T., Tyberghien, L., Harkinezhad, T., Beeckman, D.S., Braeckman, L., Vanrompay, D., 2010b, Chlamydophila psittaci zoonotic risk assessment in a chicken and turkey slaughterhouse. J Clin Microbiol 48, 3244-3250. Ecco, R., Preis, I.S., Martins, N.R.S., Vilela, A.A.R., Shivaprasad, H.L., 2009, An outbreak of chlamydiosis in captive psittacines. Braz J Vet Pathol 2, 85-90. Escalante-Ochoa, C., Ducatelle, R., Haesebrouck, F., 1998, The intracellular life of Chlamydia psittaci: how do the bacteria interact with the host cell? FEMS Microbiol Rev 22, 65-78. Everett, K.D., Bush, R.M., Andersen, A.A., 1999a, Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for the identification of organisms. Int J Syst Bacteriol 49 Pt 2, 415-440. Everett, K.D., Hatch, T.P., 1995, Architecture of the cell envelope of Chlamydia psittaci 6BC. J Bacteriol 177, 877-882. Everett, K.D., Hornung, L.J., Andersen, A.A., 1999b, Rapid detection of the Chlamydiaceae and other families in the order Chlamydiales: three PCR tests. J Clin Microbiol 37, 575-580. Fudge, A.M., 1997, A Review of Methods to Detect Chlamydia psittaci in Avian Patients. J Avian Med Surg 11, 153-165. Gaede, W., Reckling, K.-F., Schliephake, A., Missal, D., Hotzel, H., Sachse, K., 2010, Detection of Chlamydophila caviae and Streptococcus equi subsp. zooepidemicus in horses with signs of rhinitis and conjunctivitis. Vet Microbiol 142, 440-444. Gaede, W., Reckling, K.F., Dresenkamp, B., Kenklies, S., Schubert, E., Noack, U., Irmscher, H.M., Ludwig, C., Hotzel, H., Sachse, K., 2008, Chlamydophila psittaci infections in humans during an outbreak of psittacosis from poultry in Germany. Zoonoses Public Health 55, 184-188. Gasparini, J., Erin, N., Bertin, C., Jacquin, L., Vorimore, F., Frantz, A., Lenouvel, P., Laroucau, K., 2011, Impact of urban environment and host phenotype on the epidemiology of Chlamydiaceae in feral pigeons (Columba livia). Environ Microbiol 13, 3186–3193. Gaydos, C.A., Quinn, T.C., Bobo, L.D., Eiden, J.J., 1992, Similarity of Chlamydia pneumoniae strains in the variable domain IV region of the major outer membrane protein gene. Infect Immun 60, 5319-5323. Geens, T., Desplanques, A., Van Loock, M., Bonner, B.M., Kaleta, E.F., Magnino, S., Andersen, A.A., Everett, K.D.E., Vanrompay, D., 2005a, Sequencing of the Chlamydophila psittaci ompA Gene Reveals a New Genotype, E/B, and the Need for a Rapid Discriminatory Genotyping Method. J Clin Microbiol 43, 2456-2461. Geens, T., Dewitte, A., Boon, N., Vanrompay, D., 2005b, Development of a Chlamydophila psittaci species-specific and genotype-specific real-time PCR. Vet Res 36, 787-797. Gilardi, K.V., Lowenstine, L.J., Gilardi, J.D., Munn, C.A., 1995, A survey for selected viral, chlamydial, and parasitic diseases in wild dusky-headed parakeets (Aratinga weddellii) and tui parakeets (Brotogeris sanctithomae) in Peru. J Wildl Dis 31, 523-528. Harkinezhad, T., Geens, T., Vanrompay, D., 2009, Chlamydophila psittaci infections in birds: a review with emphasis on zoonotic consequences. Vet Microbiol 135, 68-77. Harkinezhad, T., Verminnen, K., Van Droogenbroeck, C., Vanrompay, D., 2007, Chlamydophila psittaci genotype E/B transmission from African grey parrots to humans. J Med Microbiol 56, 1097-1100. Heddema, E.R., Ter Sluis, S., Buys, J.A., Vandenbroucke-Grauls, C.M., van Wijnen, J.H., Visser, C.E., 2006a, Prevalence of Chlamydophila psittaci in fecal droppings from feral pigeons in Amsterdam, The Netherlands. Appl Environ Microbiol 72, 4423-4425. Heddema, E.R., van Hannen, E.J., Duim, B., de Jongh, B.M., Kaan, J.A., van Kessel, R., Lumeij, J.T., Visser, C.E., Vandenbroucke-Grauls, C.M.J.E., 2006b, An outbreak of psittacosis due to Chlamydophila psittaci genotype A in a veterinary teaching hospital. J Med Microbiol 55, 1571-1575. Heddema, E.R., van Hannen, E.J., Duim, B., Vandenbroucke-Grauls, C.M., Pannekoek, Y., 2006c, Genotyping of Chlamydophila psittaci in human samples. Emerg Infect Dis 12, 1989-1990. Herrmann, B., Persson, H., Jensen, J.K., Joensen, H.D., Klint, M., Olsen, B., 2006, Chlamydophila psittaci in Fulmars, the Faroe Islands. Emerg Infect Dis 12, 330-332. Hewinson, R.G., Griffiths, P.C., Bevan, B.J., Kirwan, S.E., Field, M.E., Woodward, M.J., Dawson, M., 1997, Detection of Chlamydia psittaci DNA in avian clinical samples by polymerase chain reaction. Vet Microbiol 54, 155-166. Hinton, D.G., Shipley, A., Galvin, J.W., Harkin, J.T., Brunton, R.A., 1993, Chlamydiosis in workers at a duck farm and processing plant. Aust Vet J 70, 174-176. Hoelzle, L.E., Hoelzle, K., Wittenbrink, M.M., 2003, Expression of the major outer membrane protein (MOMP) of Chlamydophila abortus, Chlamydophila pecorum, and Chlamydia suis in Escherichia coli using an arabinose-inducible plasmid vector. J Vet Med B Infect Dis Vet Public Health 50, 383-389. Hughes, E.S., Shaw, K.M., Ashley, R.H., 2001, Mutagenesis and Functional Reconstitution of Chlamydial Major Outer Membrane Proteins: VS4 Domains Are Not Required for Pore Formation but Modify Channel Function. Infect Immun 69, 1671-1678. Johns, J.L., Luff, J.A., Shooshtari, M.P., Zehnder, A.M., Borjesson, D.L., 2009, What is your diagnosis? Blood smear from an injured red-tailed hawk. Vet Clin Pathol 38, 247-252. Kaleta, E.F., Taday, E., 2003, Avian host range of Chlamydophila spp. based on isolation, antigen detection and serology. Avian Pathology 32, 435-462. Kaltenboeck, B., Kousoulas, K.G., Storz, J., 1993, Structures of and allelic diversity and relationships among the major outer membrane protein (ompA) genes of the four chlamydial species. J Bacteriol 175, 487-502. Laroucau, K., de Barbeyrac, B., Vorimore, F., Clerc, M., Bertin, C., Harkinezhad, T., Verminnen, K., Obeniche, F., Capek, I., B
摘要: 鸚鵡披衣菌為絕對細胞寄生性之格蘭氏陰性細菌,目前已知可以感染來自於30個目的467個鳥種,依據其主要外膜蛋白(Major outer membrane protein;MOMP)的ompA(Outer membrane protein A)基因序列分析,可以將鸚鵡披衣菌分成9個基因型,分別為基因型A - F、E/B、M56及WC。而近年來在各國間分別出現人類接觸鸚鵡鳥類、鴿子及鴨隻而感染鸚鵡披衣菌的病例出現,顯示在公共衛生方面有必要瞭解台灣各個鳥種間的鸚鵡披衣菌盛行率。本調查研究以水禽類、鸚鵡鳥類、鳩鴿科鳥類及野生鳥類為主,進行鸚鵡披衣菌的盛行率調查以及其基因型的分析,結果在2010年間水禽類的盛行率為12.7%(146/1148),而18株鸚鵡披衣菌經基因型分析結果發現序列分為兩個部分,且皆為非典型基因型的鸚鵡披衣菌;而2010年1月至2011年6月間鸚鵡鳥類的盛行率為3.1%(16/514),其中9株鸚鵡披衣菌的基因型皆為genotype A;而2009年1月至2011年6月間鳩鴿科鳥類的盛行率為10.1%(8/79),而野生鳥類的盛行率為2.2%(14/650),當中4株鳩鴿科鳥類的鸚鵡披衣菌基因型皆為genotype B,然而在野生鳥類中1株黑冠麻鷺及1株五色鳥的樣本無法進行鸚鵡披衣菌的基因型分析,因此僅分析ompA之部分序列VDI(Variable domain I),結果發現兩株序列皆為非典型披衣菌種別。本調查研究顯示台灣的水禽類、鸚鵡鳥類、鳩鴿科鳥類及野生鳥類都有鸚鵡披衣菌的病原存在,其中鸚鵡鳥類及鳩鴿科鳥類的鸚鵡披衣菌基因型在國外皆曾出現人被感染的病例,因此在公共衛生上是值得重視的議題;此外在水禽類、黑冠麻鷺及五色鳥出現非典型的披衣菌,皆需進一步探討其病原性以評估這類非典型的披衣菌在各種鳥種族群中扮演的角色,然而在尚未確立前仍然不容忽視非典型的披衣菌在公共衛生上的威脅性。
Chlamydophila psittaci (C. psittaci), an obligate intracellular bacterium which causes avian chlamydosis in 467 avian species and 30 orders, can be divided into nine genotypes (A to F, E/B, M56, and WC) according to its outer membrane protein A (ompA) gene. A number of reports have demonstrated that humans can be infected C. psittaci via contacting infected psittacine pet birds, pigeons, and domestic waterfowls. Therefore, the current prevalence status of C. psittaci in birds in Taiwan is critical for public health. In the current study, we investigated the prevalence of C. psittaci in domestic waterfowls, psittacine birds, columbidae birds and non-psittacine birds in Taiwan. The positive rate of C. psittaci in domestic waterfowls was 12.7% (146/1148) in 2010. In psittacine birds, 3.1% (16/514) of samples were positive for C. psittaci between January 2010 and June 2011. In columbidae birds and non-psittacine birds, the positive rates of C. psittaci were 10.1% (8/79) and 2.2% (14/650), respectively. Genotype A was detected in 9 psittacine birds, and genotype B were detected in 4 columbidae birds. However, the phylogenetic analysis of partial ompA gene from 18 domestic waterfowl strains revealed that there were two atypical genotype clusters outside the currently recognized genotypes of C. psittaci. Furthermore, two atypical strains of Chlamydiaceae were detected by ompA variable domain I (VDI) sequence analysis from one Gorsachius melanolophus and one Megalaima nuchalis. To sum up, the results indicated that C. psittaci-infected psittacine birds and columbidae birds may be a potential risk factor for transmitting the disease from pet birds and pigeons to humans. Further studies need to be done for the pathogenesis of these atypical Chlamydiaceae in different avian species and the investigation of their capability to cause public health issue.
URI: http://hdl.handle.net/11455/12867
其他識別: U0005-1101201215251900
文章連結: http://www.airitilibrary.com/Publication/alDetailedMesh1?DocID=U0005-1101201215251900
Appears in Collections:獸醫學系所

文件中的檔案:

取得全文請前往華藝線上圖書館



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.