Please use this identifier to cite or link to this item:
Natural and experimental studies on sulphur intoxication in pigs.
hepatic cell necrosis
硫磺混合飼料一次餵飼 200g、 100g、50g、及多次 50g 6 天連續投與處
Sulphur is usually used as floor disinfectant in many local pig farms in Taiwan. An incidence of sulphur intoxication was obseved in a pig farm. The mortality was about 10%. The main lesions were necrosis of portal triads and accumulation of edematous fluid and inflammatory infiltration in the submucosal layers of the colon. In pigs sulphur intoxication has never been reported before all study. In experiment, sulphur mixed in the feed with a vaeied dose of 200g, 100g and 50g/Kg body weight, and six doses of 50g, were fed to four groups of pigs. The same lesions as those seen in the natural cases were found in varying degrees dependent on the different doses. By scanning electron microscopic examination, sulphur particles were seen on superficial surface of necrotic cell debris taken from colon membrane of Sulphur-fed pigs. The mitochondria of mucosal membrane revealed swelling and necrosis under transmitting electron microscopic examination. By Gas Chromatograph/Mass Spectrometer was signal peak correlating to sulfurous acid was observed in the extract of affected liver. This was suggested that the mechanism of sulphur intoxication was the result of direct damage of peripheral zone of hepatic lobules by the product of sulfurous acid from colon.
|Appears in Collections:||獸醫學系所|
Show full item record
TAIR Related Article
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.