Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/14348
標題: 分散式固相萃取結合注射口衍生化氣相層析串聯質譜術於水中全氟化合物檢測之研究
Determination of Perfluorinated Compounds in Water by Dispersive SPE Combined with In-port Derivatization-Gas Chromatography-Tandem Mass Spectrometry
作者: 許婉愉
Hsu, Wan-Yu
關鍵字: 全氟化合物
dispersive solid-phase extraction
氣相層析串聯質譜
分散式固相萃取
注射口衍生化
perfluorinated compound
gas chromatography-tandem mass spectrometry
in-port derivatization
出版社: 化學系所
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摘要: 本研究利用分散式固相萃取結合注射口衍生化的方式,藉由氣相層析串聯質譜技術(GC-MS/MS)同時進行水樣品中五種全氟化合物的檢測分析。分析物分別為全氟羧酸類之全氟庚酸、全氟辛酸、全氟壬酸、全氟癸酸和全氟磺酸類之全氟辛磺酸。本研究為最先使用氣相層析串聯質譜術同時針對此兩類全氟化合物,並利用同位素標準品進行定量分析。實驗結果顯示樣品以分散式固相萃取法進行萃取,於5毫升水樣品中,添加3.5克甲酸銨,萃取溶劑為含0.1%甲酸及30%衍生化試劑之乙酸乙酯溶液,並選用celite做為淨化用之吸附劑,吸附劑添加量為30毫克,有最佳之萃取與淨化效果。此方法利用離子對試劑Tetrabutyl ammonium hydroxide 30‧hydrate於氣相層析注射口中高溫衍生化,再以氣相層析串聯質譜儀偵測。五種分析物之偵測線性範圍在0.05-100 ng/mL之間,線性相關係數皆在0.9900以上,偵測極限在0.5 pg/mL至3.8 pg/mL之間,定量極限則在1.6 pg/mL至12.5 pg/mL之間。將所提檢測方法應用於真實河川樣品之分析,檢測出全氟化合物的濃度為0.1 ng/mL至78 ng/mL 之間,顯示此方法是一具快速、簡單、準確等優點於水溶液中微量全氟化合物含量之分析,所開發方法可做為水溶液中微量全氟化合物分析方法之參考。
URI: http://hdl.handle.net/11455/14348
其他識別: U0005-2607201209303000
文章連結: http://www.airitilibrary.com/Publication/alDetailedMesh1?DocID=U0005-2607201209303000
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