Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/23200
標題: 臺灣防己科藥用植物資源之研究
Studies on the medicinal plant resource of Menispermaceae in Taiwan
作者: 江孟玲
Chiang, Mon-Ling
關鍵字: Menispermaceae
防己科
morphological
characteristics
DNA polymorphic
medicinal resource
形態特徵
核酸多形性
藥用資源
出版社: 生命科學院碩士在職專班
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摘要: 臺灣原生防己科(Menispermaceae )植物共有6屬13種2變種,大都為木質藤本,僅樟葉木防己(Cocculus laurifolius DC.)1種為直立灌木,分布於臺灣地區海拔1,500公尺以下的林緣灌叢或路邊開闊地,其中12種2變種為有文獻紀錄的藥用植物。這些防己科植物常被山區的民眾視為傳統鄉野用藥,其療效的記載多為消炎、止痛、消腫、利尿、降血壓,臨床用途包括治療蛇毒、風濕性關節炎、跌打損傷等。學界近年來有相當多有關防己科植物活性成分的藥理研究,國內多集中在對該科粉防己鹼(tetrandrine)的活性藥理研究;惟臺灣目前中醫師所使用防己科藥材多為中國大陸進口。 本研究基於本土防己科藥用資源永續利用的觀點,整理出臺灣防己科藥用植物的分布、蘊藏量和物候,同時彙整臺灣防己科藥用植物主要活性成分和藥理特性。由於臺灣的氣候非常適合木防己(Cocculus orbiculatus(L.)DC.)和千金藤(Stephania japonica (Thunb.ex Murray) Miers var.japonica)之生長,終年都能開花結果,故其分布廣泛且蘊藏量相當豐富。利用RAPD法分析研究,探討木防己、千金藤及蘭嶼千金藤(Stephania merrillii Diels)之遺傳結構變異情節,結果發現其確實受到地理區域之影響,造成彼此歧異分化的遺傳漂變現象。且由於臺灣原生防己科藥用植物已隨人為土地利用的開發而破壞其生育地,逐有漸擴大區隔的趨勢,這對防己科植物之基因庫及其藥用經濟效益等資源的永續利用相當不利,誠有必要藉此提出復育本科藥用植物之建議及呼籲。
There are 6 genera 13 species and 2 varieties belonging to the Menispermaceae to be indigenous in Taiwan. Almost all of them are woody lianas, except Cocculus laurifolius DC. to be an erect shrub. Those plants mainly grow in the regions below the elevation of 1,500 meters, occurred in the bushes of forest edge or along the open place of roadside. 12 species and 2 varieties of the plants are recorded as a herbal medicine. Those plants have often been used by the people in mountain areas as a traditional folk remedy. The curative effects as recorded are primarily as antiphlogistic, anodyne, resolutive, diuretic, and hypertension-reducer. Clinically, they are used as treatments for venin, rheumarthritis, and every kind of bruises and wounds. In recent years, the extensive research about pharmacological active ingredients of the Menispermaceae had been proceeded. In Taiwan, such research has mainly focused on the pharmacological activities of tetrandrine found in the plants of this family. However, most of the Menispermaceous herbs used by the Chinese herb doctors in Taiwan are chiefly imported from the mainland China. Based on a sustainable use of the native plants of Menispermaceae and their pharmacological resources, the study traces the distribution, abundance, and phenology of those herbal plants in Taiwan, and compiles the active ingredients and pharmacological properties of them. The climate of Taiwan is suitable for the growth of Cocculus orbiculatus (L.) DC. and Stephania japonica (Thunb. ex Murray) Miers var. japonica, which blossom and fruit at all the year round, so they distribute thoughout the Island and their reserves are relatively abundant. Employing the RAPD analysis , the result infers that the genetic variations of Cocculus orbiculatus (L.) DC., Stephania japonica (Thunb. ex Murray) Miers var. japonica, and S. merrillii Diels have surely been influenced by the geographical isolation. Nonetheless, owing to land exploitation, the sites for the native Menispermaceous herbal plants have largely been destroyed, and the gap of geographical discrimination has increasingly enlarged. Such development is detrimental for both the gene pool and the pharmacological economy of those plants. In conclusion, this study suggests that it should be necessary to restore the breeding and growing of the native Menispermaceous plants in order to develop their sustainable application.
URI: http://hdl.handle.net/11455/23200
其他識別: U0005-1307200610022400
文章連結: http://www.airitilibrary.com/Publication/alDetailedMesh1?DocID=U0005-1307200610022400
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