Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/24745
標題: 乳酸菌之培養條件對胞外多醣體產量 與特性之影響
Effect of fermentation conditions on production and characteristic of exopolysaccharide from lactic acid bacteria
作者: 翁嘉鞠
Chia-Chu, Weng
關鍵字: lactic acid bacteria
乳酸菌
exopolysaccharide
bile salts
胞外多醣
膽鹽
出版社: 動物科學系所
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摘要: Lactobacillus acidophilus BCRC 14079、Lactobacillus delbrueckii subsp. bulgaricus BCRC 10696及Lactobacillus rhamnosus BCRC 16000在以MRSL (MRS+ 2% lactose)為培養基時,乳酸菌的胞外多醣與菌株生長期有一相關性,胞外多醣於菌株進入對數期開始累積,在穩定期末達最高的多醣生成量,S. thermophilus BCRC 14085在培養後第28小時達最高的多醣生成量,在培養後第28至32小時左右,當菌株邁入死滅期時,多醣量均下降。在以篩選產黏菌株的牛乳培養基(MYPL)中,各菌株在穩定期末,都有最高量的多醣生成,產量也高於以MRSL為培養基者。菌株於MRSL培養基於增殖的第8或第12小時有高分子量多醣(106)的生成,但在MYPL培養基中,則均為低分子量多醣(<103)的生成。隨著菌株多醣生成量的增加,菌株對培養基中膽鹽降低量也增加,可能是胞外多醣對膽鹽的吸附作用,使其隨菌體細胞離心析出。菌株的膽鹽去結合能力也隨其進入對數生長期增加,以在MRSL培養基菌株有較佳的膽鹽水解活性。菌株在MYPL培養基中,於耐酸、膽鹽及消化道試驗中存活率低。
The production of exopolysaccharide by lactic acid bacteria is growth-associated in MRSL (MRS+2% lactose) medium. A higher exopolysaccharide production can be found in MYPL medium (9% skim milk + 0.35% yeast extract+ 0.35% peptone+ 5% lactose), compared to the MRSL medium. The highest exopolysaccharide production can be achieved by the end of stationary phase in both media. There is high-molecular-mass exopolysaccharide synthesis in MRSL medium after incubation for 8 to 12 hours. The level of sodium cholate in the medium decreases as the cell growth and exopolysaccharide production increase, suggesting that there is an exopolysaccharide binding effect to the sodium cholate. Deconjugation activity of lactic acid bacteria is maximum in the late exponential phase of growth. The cell survival rate of lactic acid bacteria under the stress of acid, bile or gastrointestinal tract is low in MYPL medium.
URI: http://hdl.handle.net/11455/24745
其他識別: U0005-0506200718481700
文章連結: http://www.airitilibrary.com/Publication/alDetailedMesh1?DocID=U0005-0506200718481700
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