Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/2475
標題: 利用流體聚焦生成微液滴與混合之實驗研究
Formation of droplet and mixing through flow-focusing on stationary and rotating microfluidics
作者: 陳煜壬
Chen, Yu-Jen
關鍵字: Droplet
微液滴
Flow-focusing
U-type channel
流體聚焦
U型流道
出版社: 機械工程學系所
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摘要: 本研究分別以壓力及離心力驅動微流道流體,利用流體聚焦(flow-focusing)方式使消散相流體頸縮,生成由兩種液體混合的微液滴,觀察其混合效率。為了迅速增強液滴內的混合效率,流體聚焦流道下游增加製作U型流道之混合區。我們使用黃光微影製程製作母模,並利用PDMS轉印微流道結構。實驗流體以油為連續相流,水為消散相流,產生油包水(water-in-oil)的微液滴,經由可視化設備觀察液滴生成與混合現象。在壓力驅動實驗中,連續相與消散相流道寬度為100 μm,固定消散相流率為0.01 ml/hr,調整連續相流率於0.02 - 0.06 ml/hr的範圍,可產生成直徑114~135 μm的液滴。在流體聚焦處剛生成的液滴,由於頸縮作用可提供60 %的預混合效率,再搭配下游U型混合區,混合效率可迅速提升至95 %。在離心力驅動實驗中,連續相與消散相流道寬度分別為300 與200 μm,可生成微液滴的範圍為400-700 rpm。在轉速400、500及700 rpm下,可生成液滴直徑分別為402、452與900 μm,搭配U型混合區,混合效率可達80%以上。
Experiments were carried out to investigate fluid mixing within droplets generated using the flow-focusing method in microchannels. Polydimethylsiloxane (PDMS) was employed to fabricate the microchannels using the photolithography technique. The microchannels were composed of a Y-junction to bring two types of liquids into contact, a cross-junction to from droplets and a U-shaped channel to further enhance the droplet mixing. Oil as a continuous-phase flow and water as a dispersed-phase flow were injected into the channels by syringe pumps or by centrifuge on a rotating disk. In the pressure-driven microchanels that had the same width of 100 μm, the continuous-phase flow rate was varied between 0.02-0.06 ml/hr (at a constant dispersed-phase flow rate of 0.01 ml/hr) to produce droplets having diameters ranging between 114 to 135 μm. It is found that the mixing efficiency can reach as much as 60% when the droplet is just formed via flow focusing and the downstream U-shaped channel easily raises it to around 95%. In the centrifuge-driven microfluidcs that consists of a 300-μm-width continuous-phase channel and a 200-μm-width channel dispersed-phase channel, the droplets can be formed only at a certain range of rotational speed, 402-452 μm in diameter at 400-500 rpm and 900 μm in diameter at 700 rpm. It is also found that mixing efficiency can be largely increased to about 85% for the channels with U-shaped structure.
URI: http://hdl.handle.net/11455/2475
其他識別: U0005-1908201010290300
文章連結: http://www.airitilibrary.com/Publication/alDetailedMesh1?DocID=U0005-1908201010290300
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