Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/32653
標題: Mammary carcinoma with sebaceous differentiation in a dog
作者: Chang, S.C.
廖俊旺
Liao, J.W.
Wong, M.L.
Lai, Y.S.
Liu, C.I.
張仕杰
關鍵字: canine
mammary carcinoma
sebaceous carcinoma
sebaceous metaplasia
breast
gland
期刊/報告no:: Veterinary Pathology, Volume 44, Issue 4, Page(s) 525-527.
摘要: This report describes an invasive mammary carcinoma with a rare distinctive feature characterized by sebaceous differentiation of tumor cells. This tumor occurred in a 10-year-old female mixed breed dog. The patient had two masses in the left fifth mammary gland. Grossly, the masses were Firm, whitish to light brown, and superficially ulcerated. On cut surface, they were multilobulated with foci of necrosis. Microscopically, the tumors were composed of two distinctive neoplastic components, intraductal papillary adenocarcinoma and sebaceous carcinoma. The regions of sebaceous tumor were clumped separately, contained well-developed sebaceous cells and keratinized epithelial cells, and were surrounded by few to several layers of basaloid cells. The cells with abundant foamy cytoplasm that resembled sebaceous cells were also found within the intraductal papillary-like nests of mammary carcinoma, providing evidence of sebaceous metaplasia. Sebaceous differentiation in a mammary gland tumor is possible, because skin appendages and ductal apparatus of the mammary gland share a common anlagen. This tumor had an aggressive behavior with lymphatic metastasis. Consequentially, the dog had a poor prognosis.
URI: http://hdl.handle.net/11455/32653
ISSN: 0300-9858
文章連結: http://dx.doi.org/10.1354/vp.44-4-525
Appears in Collections:獸醫學系所

文件中的檔案:

取得全文請前往華藝線上圖書館



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.