Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/34036
DC FieldValueLanguage
dc.contributor.authorChen, C.R.en_US
dc.contributor.author張傑明zh_TW
dc.contributor.authorLee, Y.N.en_US
dc.contributor.authorChang, C.M.J.en_US
dc.contributor.authorLee, M.R.en_US
dc.contributor.authorWei, I.C.en_US
dc.contributor.author李茂榮zh_TW
dc.date2007zh_TW
dc.date.accessioned2014-06-06T07:47:04Z-
dc.date.available2014-06-06T07:47:04Z-
dc.identifier.issn0368-1653zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/34036-
dc.description.abstractThis work has examined the hot-pressurized fluid extraction of seven flavonoids, caffeic acid phenethyl ester and four phenolic acids from Brazilian propolis lumps generating, during the process, fat- and water-soluble extracts. The solid content of water-soluble extract obtained by hot-pressurized water in the presence of 29% natural surfactant was 35.2 mg/mL and was 44% greater than that obtained without natural surfactant. Furthermore the amount of the seven flavonoids and caffeic acid phenethyl ester in the fat-soluble extract exceeded those in the water-soluble sample while, on the other hand, the amount of the four phenolic acids in the water-soluble extract was more than those in the fat-soluble extract. Our findings show that the total solid content and the amount of these 12 active compounds produced by the emulsified hot-pressurized water are 36% and 7% higher, respectively, than those produced by emulsified water at atmospheric pressure. The EC50 value of the free radical scavenging activity of 1,1-diphenyl-2-picrythydrazyl of the emulsified hot-pressurized water extract was the lowest, and presented the strongest anti-oxidation ability among all the extracts. In vitro cytotoxicity indicated that the water-soluble extract strongly suppressed the growth of leukemia (HL-60, U937), lung cancer (A549, CH27) and liver cancer (Hep G2, Hep 3B) cells in a concentration-dependent behavior. (C) 2007 Taiwan Institute of Chemical Engineers. Published by Elsevier B.V. All rights reserved.en_US
dc.language.isoen_USzh_TW
dc.relationJournal of the Chinese Institute of Chemical Engineersen_US
dc.relation.ispartofseriesJournal of the Chinese Institute of Chemical Engineers, Volume 38, Issue 3-4, Page(s) 191-196.en_US
dc.relation.urihttp://dx.doi.org/10.1016/j.jcice.2007.04.004en_US
dc.subjecthot-pressurized fluidsen_US
dc.subjectwater-soluble propolis extractsen_US
dc.subjectflavonoidsen_US
dc.subjectphenolic acidsen_US
dc.subjectanti-oxidation abilityen_US
dc.subjectin vitro cytotoxicityen_US
dc.subjectchemical-compositionen_US
dc.subjectartepillin-cen_US
dc.subjectbiological-propertiesen_US
dc.subjectantioxidanten_US
dc.subjectactivityen_US
dc.subjectphenethyl esteren_US
dc.subjecttumor-cellsen_US
dc.subjectgc-msen_US
dc.subjectidentificationen_US
dc.subjectconstituentsen_US
dc.subjecttoxicityen_US
dc.titleHot-pressurized fluid extraction of flavonoids and phenolic acids from Brazilian propolis and their cytotoxic assay in vitroen_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1016/j.jcice.2007.04.004zh_TW
Appears in Collections:化學系所
文件中的檔案:

取得全文請前往華藝線上圖書館



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.