請用此 Handle URI 來引用此文件: http://hdl.handle.net/11455/34337
標題: Preparation of polypeptide via living polymerization of Z-Lys-NCA initiated by platinum complexes
作者: Peng, Y.L.
林助傑
Lai, S.L.
Lin, C.C.
關鍵字: acid-n-carboxyanhydrides
block copolypeptides
gamma-methylglutamate
nanoparticles
ligands
product
systems
cobalt
期刊/報告no:: Macromolecules, Volume 41, Issue 10, Page(s) 3455-3459.
摘要: Two novel platinum complexes, [bis(diphenylphosphino)ethane][N-((1S,2R)-2-hydroxo-1,2-diphenylethyl)-4-methyl-benzenesulfonamidato]platinum(II) [(dppe)Pt(MBS-O), 2a] and [bis(diphenylphosphino)ethane] [N-((IS,2R)-2-amido-1,2-diphenylethyl)-4-methylbenzenesulfonamidato]platinum [(dppe)Pt(MBS-NH), 2b] were synthesized and structurally characterized. Experimental results show that compound 2b is an efficient initiator toward ring opening polymerization of amino acid N-carboxyanhydride (NCA) yielding polypeptides with narrow PDIs (1.07-1.19). By comparing the activity of complex 2a with that of 2b, the mechanism for polymerization of NCA initiated by an amido-sulfonamidate is proposed.
URI: http://hdl.handle.net/11455/34337
ISSN: 0024-9297
文章連結: http://dx.doi.org/10.1021/ma7025836
顯示於類別:化學系所

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