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|標題:||Highly Efficient Cul-catalyzed N-Arylation of Azaheterocycles with Aryl Iodides Using 1,1,1-Tris(hydroxymethyl)ethane as a Tridentate O-Donor Ligand: A Shorter Route to Toloxatone and Formal Synthesis of Linezolid|
|期刊/報告no：:||Journal of the Chinese Chemical Society, Volume 57, Issue 1, Page(s) 14-18.|
|摘要:||An efficient copper-catalyzed N-arylation of azaheterocycles with aryl iodides using 1,1,1-tris(hydroxymethyl)ethane as a tridentates O-donor ligand has been accomplished in good to excellent yields. Moreover, this highly efficient catalyst system has been successfully demonstrated to one-step synthesis of toloxatone and a shorter route to formal synthesis of linezolid in good yields.|
|Appears in Collections:||化學系所|
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