請用此 Handle URI 來引用此文件: http://hdl.handle.net/11455/34759
標題: An Analyte Derivatization Approach for Improved Electrochemical Detection Amoxicillin
作者: Chiu, M.H.
曾志明
Chang, J.L.
Zen, J.M.
關鍵字: Amoxicillin
Manganese dioxide
Screen-printed carbon electrode
Sensors
Environmental chemistry
beta-lactam antibiotics
carbon-paste electrode
tandem
mass-spectrometry
liquid-chromatography
spectrophotometric
determination
voltammetric determination
injection-analysis
bovine-milk
ampicillin
plasma
期刊/報告no:: Electroanalysis, Volume 21, Issue 14, Page(s) 1562-1567.
摘要: Ibis paper introduces an interesting analyte derivatization approach for improved electrochemical detection of amoxicillin (one of the most frequently used P-lactam antibiotics). It is based on the well-known chemical conversion of catechols to o-quinones by MnO(2) that can be subsequently easily determined by electrochemical reduction at inexpensive screen-printed carbon electrodes. The MnO(2) reactor is essential to the proposed amperometric sensor not only to increase the electroactivity but also to achieve the detection selectivity. Under the optimized conditions of applied potential = 0.0 V vs. Ag/AgCl and flow rate 500 mu L/min, the measurement range was over 3 orders of magnitude with a detection limit (S/N= 3) of 17 nM.
URI: http://hdl.handle.net/11455/34759
ISSN: 1040-0397
文章連結: http://dx.doi.org/10.1002/elan.200904604
顯示於類別:化學系所

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