請用此 Handle URI 來引用此文件: http://hdl.handle.net/11455/35131
標題: Docking study of the precursor peptide of matoparan onto its putative processing enzyme, dipeptidyl peptidase IV: a revisit to molecular ticketing
作者: Jang, S.
李豐穎
Chung, T.Y.
Shin, J.
Lin, K.L.
Tzen, J.T.C.
Li, F.Y.
曾志正
關鍵字: Molecular docking
Replica exchange molecular dynamics (REMD)
Mastoparan
crystal-structure
xenopus-laevis
wasp venom
mastoparan
protein
dynamics
inhibitors
release
binding
toxin
期刊/報告no:: Journal of Computer-Aided Molecular Design, Volume 24, Issue 3, Page(s) 213-224.
摘要: Stepwise-cleavage process of promastoparans to reach maturity was investigated theoretically by combining ab initio folding and unbounded docking. The comparison between the structures of the promastoparans both before and after docking were examined along with the hydrogen bonding interaction pattern between the dipetidyl peptidase IV (DPPIV) and promastoparans to reveal how the endpoint of this stepwise cleavage is recognized among these promastoparans with highly resemble amino acid sequences. The current approach of folding and docking study provides structural insight on the stepwise cleavage process.
URI: http://hdl.handle.net/11455/35131
ISSN: 0920-654X
文章連結: http://dx.doi.org/10.1007/s10822-010-9327-7
顯示於類別:化學系所

文件中的檔案:
沒有與此文件相關的檔案。


在 DSpace 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。