Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/35566
標題: 液態生物反應器氧氣傳導係數之建模與測試
Modeling and Testing for Oxygen Transfer Coefficient of the Liquid Bioreactor
作者: 余見仁
Yu, Jian-Ren
關鍵字: oxygen transfer
氧氣傳遞
liquid bioreactor
volumetric mass transfer coefficient
modeling
液態生物反應器
體積質傳係數
建模
出版社: 生物產業機電工程學系所
引用: 1.清華大學化工系。2003年。氣泡塔與氣舉式反應器。新竹:清華大學。網址:http://www.che.nthu.edu.tw/lesson/class/teach/mpeg/teach/A5.htm。上網日期:2006-11-12。 2.陳加忠。2004年。生物反應器的關鍵技術。國立中興大學生物產業機電工程學研究所,生物系統工程研究室。台中。42–63。 3.王樹青、元英進。2001年。生物過程自動化技術。化學工業出版社,北京。101–106。 4.吳文騰主編。2002年。生物產業技術概論。國立清華大學出版社:新竹。275-299。 5.胡振奎。2007年。以軟體感測器建立生物反應器內其生物生長模式。碩士論文。台中:中興大學生物產業機電工程學研究所。 6.Moore, J.W. Stanitski, C.L. and Jurs, P.C. 2002. Chemistry The Molecular Science. 693-694. Orlando: Harcourt. 7.F. Veglio, F. Beolchini and S. Ubaldini. 1998. Empirical models for oxygen mass transfer:a comparison between shake flask and lab-scale fermentor and application to manganiferous ore bioleaching. Process Biochemistry 33(4):367-376. 8.Tibor Anderlei and Jochen Buchs. 2001. Device for sterile online measurement of oxygen transfer rate in shaking flasks. Biochemical Engineering Journal 7:157-162. 9.Yuan-Shuai Liu, Jian-Yong Wu, Kwok-ping Ho. 2006. Characterization of oxygen transfer conditions and their effects on Phaffia rhodozyma growth and carotenoid production in shake-flask cultures. Biochemical Engineering Journal 27:331–335. 10.K. Pouliot, J. Thibault, A. Garnier, and G. Acuna Leiva. 2003. KLa Evaluation during the course of fermentation using data reconciliation techniques. Bioprocess Engineering 23:565-573. 11.L. Poughon, D. Duchez, J.F. Cornet, and C.G. Dussap. 2003. KLa determination:comparative study for a gas mass balance method。Bioprocess and Biosystems Engineering 25:341-348. 12.U. Maier and J. Buchs. 2001. Characterisation of gas-liquid mass transfer in shaking bioreactors. Biochemical Engineering Journal 7:99-106. 13.U. Maier, M. Losen, and J. Buchs. 2004. Advances in understanding and modeling the gas–liquid mass transfer in shake flasks. Biochemical Engineering Journal 17:155-167. 14.M. Deront, F. M. Samb, Nevenka Adler, and Paul Peringer. 1998. Volumetric oxygen mass transfer coefficient in an upflow cocurrent packed-bed bioreactor. Chemical Engineering Science 53(7):1321-1330. 15.Atul Gupta and Govind Rao. 2003. A study of oxygen transfer in shake Flasks Using a Non-invasive Oxygen Sensor. Biotechnology and Bioengineering 84:351-358. 16.Richard D. Guarino et al. 2004. Method for Determining Oxygen Consumption Rates of Static Cultures From Microplate Measurements of Pericellular Dissolved Oxygen Concentration. Biotechnology and Bioengineering 86:775-787. 17.Belma Ozbek and Sevgi Gayik. 2001. The studies on the oxygen mass transfer coefficient in a bioreactor. Process Biochemistry 36:729-741.
摘要: 在評估生物反應器內部環境時,最重要的指標是氧氣傳導速率。在探討氧氣傳遞時,描述氧氣質傳模式有很多種,其中有ASCE氧氣質傳模式、McWhirter and Hutter氧氣質傳模式及off-gas氧氣質傳模式等相關理論。 本實驗是採用三種氧氣質傳模式,分別為ASCE氧氣質傳模式、修正McWhirter and Hutter氧氣質傳模式和off-gas氧氣質傳模式。並藉由量測生物反應器內部的溶氧和氧氣變化量,來測試三種氧氣質傳模式。
It is an important variable that is oxygen transfer rate to evaluate the internal part of the bioreactor. There has many oxygen transfer models to study oxygen transfer. For example, ASCE oxygen mass transfer, McWhirter and Hutter oxygen mass transfer model and off-gas mass transfer model are the relevant theory. The study introduces three kinds of oxygen mass transfer model. They are ASCE oxygen mass transfer model, modified McWhirter and Hutter oxygen mass transfer model and off-gas mass transfer model. A method is available to measure dissolved oxygen and oxygen in the bioreactor, and to test three kinds of oxygen mass transfer model.
URI: http://hdl.handle.net/11455/35566
其他識別: U0005-0408200914432500
文章連結: http://www.airitilibrary.com/Publication/alDetailedMesh1?DocID=U0005-0408200914432500
Appears in Collections:生物產業機電工程學系

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