Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/3747
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dc.contributor戴憲宏zh_TW
dc.contributor詹立行zh_TW
dc.contributor莊宗原zh_TW
dc.contributor林慶炫zh_TW
dc.contributor.advisor鄭如忠zh_TW
dc.contributor.author羅佳豪zh_TW
dc.contributor.authorLo, Chia-Haoen_US
dc.contributor.other中興大學zh_TW
dc.date2010zh_TW
dc.date.accessioned2014-06-06T05:32:41Z-
dc.date.available2014-06-06T05:32:41Z-
dc.identifierU0005-1708200911483600zh_TW
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dc.identifier.urihttp://hdl.handle.net/11455/3747-
dc.description.abstract自組裝(self-assembly)行為是因結構之親疏水性、溶劑條件不同而產生的現象,其作用力包括:靜電作用(electrosatatic interactions)、氫鍵(hydrogen bonding)、凡得瓦力(van der Waals forces)和疏水效應(solvophobic effects)等。高分子自組裝材料多半以diblock copolymer和tribolck copolymer為主,其中也有導入樹枝狀高分子之結構,因為樹枝狀高分子具有獨特、精確和完美的奈米結構,以致於可應用在各個領域如:分子包覆及釋放、光電材料和藥物傳遞等。 樹枝狀高分子不僅提供一奈米結構之構築單元,更可利用代數作為自組裝行為之變因,本研究發展出具不同末端官能基及不同代數之啞鈴型樹枝狀高分子,實驗分成兩部份:(1)樹枝狀高分子:利用IDD (4-isocyanato-4’(3,3-dimethyl-2,4-dioxo-azetidino)diphenylmethane)為構築單元並經收歛的合成路徑發展至高代數。(2)製備dumbbell shaped dendrimer:利用市售親水性的Jeffamine ED-2003做為中間連接分子,與樹枝狀高分子進行開環加成反應。 為了探討系統的自組裝行為,實驗中藉由調控溶劑與水的比例和表面張力的測試,得知材料的臨界微胞濃度。材料在臨界微胞濃度下,透過AFM及TEM觀察材料的微胞型態,隨著樹枝狀高分子的導入及代數的增加,不僅分子內與分子間的作用力增加,也有效地提升微胞的穩定性;此外,實驗中更改變溶劑條件,證實分子於水溶液及有機溶劑中的排列情形。因此,本實驗成功製備出於特定條件下具自組裝行為之啞鈴型樹枝狀高分子。zh_TW
dc.description.abstractThe primary driving force responsible for the molecule arrangement was proposed to be the electrostatic interactions, hydrogen bonds, van der Waals forces, π-π stacking interactions and solvophobic effects. Self-assembling materials in the bulk state include liquid crystals, block copolymers, hydrogen-bonded complexes and precise control of molecular arrangements such as dendrimers. Dendritic strucutre is essential to obtain well-defined nanoscopic architectures with specific shape which are widely studied for their great potential as advanced functional materials in encapsulated systems, electro-optical areas, drug delivery, self-assembly systems, etc. Herein, we focus on a dumbbell shaped dendrimer system. The persuit of developing the dumbbell shapd dendrimers is approached in two steps:(1) dendrons: a building block, 4-isocyanato-4'(3,3-dimethyl-2,4-dioxo-azetidino)diphenylmethane(IDD) is selected to prepare two series of dendrons via a convergent route.(2)dumbbell shaped dendrimers: jeffamine ED-2003 is utilized as the coupling agent via selective ring-opening addition of azetidine-2,4-diones toward alphatic primary amines. To probe the self-assembly behavior, we utilized surface tension measurements to evaluate critical micelle concentrations. In addition, the morphology was characterized by atomic force microscopy (AFM) and transmission electron microscopy (TEM). By embedding different generations of dendrimers in the dumbbell shaped systems, the intermolecular or intramolecular interaction will would be enhanced because of the presence of interactions such as hydrogen bonding and van der Waals forces. The stability of micelles was further improved as higher generations of dendrons were incorporated. Moreover, ordered micelle morphologies were present in the water and organic solvents, respectively. Hence, these novel dumbbell shaped dendrimers with self-assembly behavior have been successfully developed in this work.en_US
dc.description.tableofcontents目錄 誌謝 I 中文摘要 II 英文摘要 III 目錄 IV 表目錄 VI 圖目錄 VII 代號說明 X 一、緒論 1 1.1 前言 1 1.2 規則樹枝狀分子(dendrimer)之簡介 2 二、文獻回顧和研究動機 5 2.1文獻回顧 5 2.1.1 Dendrimer結構與特性 5 2.1.2規則樹枝狀分子相關衍生物 9 2.1.3 樹枝狀分子與self-assembly現象 11 2.2 研究動機 14 三、實驗內容 15 3.1 實驗流程圖(圖3.1) 15 3.2 化學藥品 16 3.3 實驗儀器 19 3.4 4-isocyanat-4’(3,3-dimethyl-2,4-dioxo-azetidino)diphenylmethane (IDD)之合成(圖3.2) 21 3.5 C18系列polyurethane/malonamide規則樹枝狀聚合物之合成(圖3.3) 23 3.6 Diol系列polyurea/malonamide規則樹枝狀聚合物之合成(圖3.4) 26 3.7 Dumbbell shaped系列樹枝狀聚合物之合成(圖3.5) 29 四、結果與討論 32 4.1具反應選擇性單體IDD之合成 32 4.2收斂式polyurethane/malonamide dendrons之合成 36 4.2.1 G0.5-C18之合成與結構鑑定 36 4.2.2 G1-C18之合成與結構鑑定 38 4.2.3 G1.5-C18之合成與結構鑑定 40 4.2.4 G2-C18之合成與結構鑑定 43 4.2.5 G2.5-C18之合成與結構鑑定 45 4.3收斂式Polyurea/malonamide dendrons之合成 48 4.3.1 Diol系列之監控反應 48 4.3.2 G0.5-diol之合成與結構鑑定 49 4.3.3 G1-diol之合成與結構鑑定 51 4.3.4 G1.5-diol之合成與結構鑑定 54 4.3.5 G2-diol之合成與結構鑑定 56 4.4 Dumbbell shaped dendrimer之合成 59 4.4.1 D-G0.5-C18之合成與結構鑑定 59 4.4.2 D-G1.5-C18之合成與結構鑑定 61 4.4.3 D-G2.5-C18之合成與結構鑑定 63 4.4.4 D-G0.5-diol之合成與結構鑑定 65 4.4.5 D-G1.5-diol之合成與結構鑑定 67 4.5收斂式Poly(urethane/urea)/malonamide dendrons與dumbbell shaped dendrimers之溶解度測定 70 4.6收斂式poly(urethane/urea)/malonamide dendrons與dumbbell shaped dendrimers之熱性質分析 71 4.7啞鈴型樹枝狀高分子之表面張力測定 74 4.8啞鈴型樹枝狀高分子之表面型態觀察 75 4.9啞鈴型樹枝狀高分子之自組裝示意 84 五、結論 88 六、未來展望 89 七、參考文獻 90zh_TW
dc.language.isoen_USzh_TW
dc.publisher化學工程學系所zh_TW
dc.relation.urihttp://www.airitilibrary.com/Publication/alDetailedMesh1?DocID=U0005-1708200911483600en_US
dc.subjectdumbbell shapeden_US
dc.subject啞鈴型zh_TW
dc.subjectdendrimeren_US
dc.subjectself-assemblyen_US
dc.subject規則樹枝狀高分子zh_TW
dc.subject自組裝行為zh_TW
dc.title啞鈴型樹枝狀高分子之合成及其型態學研究zh_TW
dc.titleSynthesis and Morphology of Dumbbell Shaped Dendrimersen_US
dc.typeThesis and Dissertationzh_TW
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