Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/37706
標題: Electroacupuncture-induced pressor and chronotropic effects in anesthetized rats
作者: Liao, J.M.
劉英明
Ting, H.
Lee, S.D.
Yang, C.H.
Liou, Y.M.
Peng, M.L.
Tsai, S.J.
Lin, C.F.
Lin, T.B.
關鍵字: heart rate
blood pressure
tsusanli
hoku
stimulation
rat
acupuncture-like stimulation
sympathetic-nerve activity
blood-pressure
reflex inhibition
flow
afferents
期刊/報告no:: Autonomic Neuroscience-Basic & Clinical, Volume 124, Issue 1-2, Page(s) 18-25.
摘要: The effects of electroacupuncture (Ea) on circulatory dynamics were investigated in anesthetized rats. The arterial blood pressure (BP) and the heart rate (HR) in response to Ea stimulations at the Tsusanli point (St-36) and the Hoku point (Li-4) were tested by a low frequency Ea (2 Hz; LFEa) and a high frequency Ea (20 Hz; HFEa) with stimulation intensities 20 times the motor threshold. Neither the HR nor the BP was affected when the Tsusanli point was stimulated. Whereas, Ea stimulations at the Hoku point elicit chronotropic and pressor effects. The patterns of pressor responses caused by the LFEa were different from that of an HFEa, i.e., the LFEa elicited a tonic effect, while an HFEa had a phasic one. The HFEa-induced pressor and chronotropic effects were attenuated, while the LFEa induced effects were completely blocked by an intravenous infusion of an alpha-adrenergic blocker (moxisylyte 0.2 mg/min/kg, i.v., for 20 min). A co-infusion with alpha-and beta-adrenergic blockers (propanolol 0.2 mg/min/kg, i.v., for 20 min) completely blocked the HFEa-induced pressor and chronotropic effects. We concluded that Ea stimulations, at the Hoku acupoint, with appropriate stimulation parameters can increase and maintain BP. Furthermore, the LFEa stimulation activates sympathetic vasomotor tone, whereas the HFEa stimulation causes an additional potentiation on the sympathetic drive to the heart. (c) 2005 Elsevier B.V. All rights reserved.
URI: http://hdl.handle.net/11455/37706
ISSN: 1566-0702
文章連結: http://dx.doi.org/10.1016/j.autneu.2005.10.005
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