Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/41235
標題: Interactions between nonionic Triton X surfactants and cholesterol-containing phosphatidylcholine liposomes
作者: Chern, C.S.
邱信程
Chiu, H.C.
Yang, Y.S.
關鍵字: liposome
nonionic surfactants
structural transformation of vesicles
solubilization kinetics experiments
liposome stability ratio
sodium dodecyl-sulfate
vesicle transition
lecithin vesicles
ionic
surfactants
octyl glucoside
solubilization
mechanism
detergents
bilayers
protein
期刊/報告no:: Journal of Colloid and Interface Science, Volume 302, Issue 1, Page(s) 335-340.
摘要: Solubilization kinetics experiments were developed to study the effects of the polyethylene glycol chain length of Triton X surfactants on their interactions with the cholesterol-containing phosphatidylcholine vesicles. An empirical liposome stability ratio was used to describe the vesicle solubilization process. The effectiveness of Triton X surfactants in solubilizing vesicles decreases with increasing polyethylene glycol chain length of surfactants. It was also shown that vesicles containing the intercalated surfactant molecules with the largest number of ethylene glycol units per molecule exhibited the exceedingly retarded solubilization behavior. Independent experiments based on a thermodynamic approach provide supporting evidence for the conclusions obtained from solubilization kinetics experiments. (c) 2006 Elsevier Inc. All rights reserved.
URI: http://hdl.handle.net/11455/41235
ISSN: 0021-9797
文章連結: http://dx.doi.org/10.1016/j.jcis.2006.06.028
Appears in Collections:化學工程學系所

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