Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/41241
DC FieldValueLanguage
dc.contributor.authorChiu, H.C.en_US
dc.contributor.author邱信程zh_TW
dc.contributor.authorHsiue, T.en_US
dc.contributor.authorChen, W.Y.en_US
dc.date2004zh_TW
dc.date.accessioned2014-06-06T08:05:12Z-
dc.date.available2014-06-06T08:05:12Z-
dc.identifier.issn0032-3861zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/41241-
dc.description.abstractIn this study, dextran hydrogels were obtained by free radical copolymerization of methacrylated dextran with acrylic acid (AAc) in aqueous solution. The fractions of dissociation of AAc units within hydrogel in response to changes in pH and ionic strength of external aqueous solution were determined by FTIR-ATR spectroscopy. The influence of small ion concentration within hydrogel on the dissociation constant of AAc follows the Debye-Huckel behavior. Based on the results from the FTIR-ATR measurements, the total ion concentration difference inside and outside the hydrogel was determined according to the Donnan equilibrium theory, taking account of the counterion condensation effect quantitatively. The swelling response of hydrogels to changes in external pH and ionic strength was governed mainly by the ionic osmotic pressure due to the accumulation of diffusible ions within hydrogels. The energy balance between the osmotic and elastic retractile responses indicates the non-Gaussian behavior of elastically effective subchains with increasing swelling. (C) 2003 Elsevier Ltd. All rights reserved.en_US
dc.language.isoen_USzh_TW
dc.relationPolymeren_US
dc.relation.ispartofseriesPolymer, Volume 45, Issue 5, Page(s) 1627-1636.en_US
dc.relation.urihttp://dx.doi.org/10.1016/j.polymer.2003.12.043en_US
dc.subjectdextran hydrogelsen_US
dc.subjectdorman equilibrium theoryen_US
dc.subjectcounterion condensationen_US
dc.subjectsensitive dextran hydrogelsen_US
dc.subjectglycidyl methacrylateen_US
dc.subjectcontrolled-releaseen_US
dc.subjectenzymatic degradationen_US
dc.subjectmodel proteinen_US
dc.subjectphen_US
dc.subjectsalten_US
dc.subjectgelsen_US
dc.subjectbehavioren_US
dc.subjectdrugsen_US
dc.titleFTIR-ATR measurements of the ionization extent of acrylic acid within copolymerized methacrylated dextran/acrylic acid networks and its relation with pH/salt concentration-induced equilibrium swellingen_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1016/j.polymer.2003.12.043zh_TW
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