Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/41411
標題: Chitosan as scaffold materials: Effects of molecular weight and degree of deacetylation
作者: Hsu, S.H.
徐善慧
Whu, S.W.
Tsai, C.L.
Wu, Y.H.
Chen, H.W.
Hsieh, K.H.
關鍵字: biocompatibility
chitosan
degradation
degree of deacetylation
hydrophilicity
mechanical properties
calcium alginate
polymer surfaces
cell-adhesion
degradation
morphology
acetylation
expression
membranes
protein
chitin
期刊/報告no:: Journal of Polymer Research-Taiwan, Volume 11, Issue 2, Page(s) 141-147.
摘要: In this study, we investigated in vitro the role of the degree of deacetylation and molecular weight on some biological properties of chitosan films. The influence of different degree of deacetylation and molecular weight of chitosan on the hydrophilicity, degradation, mechanical properties and biocompatibility were evaluated. The results showed that the degree of deacetylation affected the hydrophilicity and biocompatibility of the chitosan films. The molecular weight, on the other hand. affected the rate of degradation and the mechanical properties. Chitosan with higher degree of deacetylation and molecular weight was more suitable for tissue engineering applications. Alginate could be added into chitosan to modify the rigidity and hydrophilicity of chitosan. Higher hydrophilicity, biocompatibility, and elongation were found after modification.
URI: http://hdl.handle.net/11455/41411
ISSN: 1022-9760
文章連結: http://dx.doi.org/10.1023/B:JPOL.0000031080.70010.0b
Appears in Collections:化學工程學系所

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