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標題: Biomimetic growth of apatite on electrolytic TiO2 coatings in simulated body fluid
作者: Lin, C.M.
Yen, S.K.
關鍵字: electrolytic
titanium dioxide
apatite formation
bioactive titanium metal
gel-derived titania
chemical treatment
期刊/報告no:: Materials Science & Engineering C-Biomimetic and Supramolecular Systems, Volume 26, Issue 1, Page(s) 54-64.
摘要: Titanium and titanium alloys for implants have been widely applied to the orthopaedic and dental fields, due to their excellent corrosion resistance, good mechanical properties and biocompatibility. However, the near bioinert and metallic ions release are still the major problems in the clinical failure. For these reasons, modification of biomaterials surface properties, which support bioactivity and corrosion resistance, should be one of the key objectives in the design of the next generation of orthopaedic/dental implants. Cathodic electrolytic deposition of anatase TiO2 coating has been successfully deposited on pure titanium substrate. After annealed at 300 degrees C for I h, the coating were further condensed into anatase TiO2, and gradually transformed into rutile TiO2 at 500 degrees C. The dynamic cyclic polarization tests indicated that dense and nanocrystalline anatase TiO2 coated effectively improved corrosion resistance to avoid aggression of fluoride ion. For immersion tests, the matching structure of anatase TiO2 and apatite may play an important role in the apatite fort-nation ability. Moreover, the cell culture results also indicated that nanocrystalline anatase TiO2 not only promoted cells differentiation, but also appeared more bioactive while maintaining non-toxicity. Obviously, the materials characteristics such as crystal structure, surface morphology and corrosion resistance may play an important role in the osteointegration. (c) 2005 Elsevier B.V. All rights reserved.
ISSN: 0928-4931
Appears in Collections:材料科學與工程學系



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