Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/66336
標題: 台灣沙門氏菌症的流行病學:由環境、食用豬畜產品到人
Epidemiology of Salmonella Infection in Taiwan : from Environment, Food Products of Pigs, to Humans
作者: 李宗賢
Li, Tsung-Hsien
關鍵字: Salmonella
沙門氏菌
Risk factor
Salmonella Choleraesuis
Environment
危險因子
豬霍亂沙門氏菌
環境
出版社: 獸醫公共衛生學研究所
引用: Acar JF and Moulin G. Antimicrobial resistance at farm level. Rev Sci Tech. 25(2): 775-792, 2006. Acha PN and Szyfres B. Salmonellosis. Zoonoses and communicable diseases common to man and animals, Pan American Health Organization, Washington, USA. pp.233-246. 2003. Arrus KM, Holley RA, Ominski KH, Tenuta M and Blank G. Influence of temperature on Salmonella survival in hog manure slurry and seasonal temperature profiles in farm manure storage reservoirs. Livestock Sci. 102(3): 226-236, 2006. Bangtrakulnonth A, Pornreongwong S, Pulsrikarn C, Sawanpanyalert P, Hendriksen RS, Lo Fo Wong DM and Aarestrup FM. Salmonella serovars from humans and other sources in Thail, 1993-2002. Emerg Infect Dis. 10(1): 131-136, 2004. Barber DA, Bahnson PB, Isaacson R, Jones CJ and Weigel RM. Distribution of Salmonella in swine production ecosystems. J Food Prot. 65(12): 1861-1868, 2002. Barrell RA. Isolations of salmonellas from human, food and environmental sources in the Manchester area: 1976-1980. J Hyg (Lond). 88(3): 403-411, 1982. Beran GW and Steele JH. Mammal Salmonellosis. Handbook of zoonoses, CRC Press, Washington, USA. pp.289-302,1994. Boer Ed. Update on media for isolation of Enterobacteriaceae from foods. Int J Food Microbiol. 45(1): 43-53, 1998. Bohaychuk VM, GenslerG.E, King RK, Manninen KI, Sorensen O, Wu JT, Stiles ME and McMullen LM. Occurrence of pathogens in raw and ready-to-eat meat and poultry products collected from the retail marketplace in Edmonton, Alberta, Canada. J Food Prot. 69(9): 2176-2182, 2006. Bonifield HR and Hughes KT. Flagellar phase variation in Salmonella enterica is mediated by a posttranscriptional control mechanism. J Bacteriol. 185(12): 3567- 3574. Brands DA, Inman AE, Gerba CP, Mare CJ, Billington SJ, Saif LA, Levine JF and Joens LA. Prevalence of Salmonella spp. in oysters in the United States. Appl Environ Microbiol. 71(2): 893-897, 2005. Brenner FW, Villar RG, Angulo FJ, Tauxe R and Swaminathan B. Salmonella nomenclature. J Clin Microbiol. 38(7): 2465-2467, 2000. Broide E, Shapiro M, Boldur I, Klinowski E, Kimchi AN, Gluskin Y and Scapa E. Salmonellosis: an epidemiologic study. Isr Med Assoc J. 7(2): 91-94, 2005. Bruins MJ, de Boer AM and Ruijs GJ. Gastroenteritis caused by Salmonella from pet snakes. Ned Tijdschr Geneeskd.150(41): 2266-2269, 2006. Bryan FL and MP Doyle. Health risks and consequences of Salmonella and Campylobacter jejuni in raw poultry. J Food Prot. 58: 326-344, 1995. Carter GR and Wise DJ. Enterobacteriaceae Ⅱ:Salmonella and Yersinia. Essentials of veterinary bacteriology and mycology, Iowa State Press, Iowa, US. pp.137-148, 2004. Casin I, Breuil J, Darchis JP, Guelpa C and Collatz E. Fluoroquinolone resistance linked to GyrA, GyrB, and ParC mutations in Salmonella enterica Typhimurium isolates in humans. Emerg Infect Dis. 9(11): 1455-1457. 2003. Centers for Disease Control and Prevention (CDC). Preliminary FoodNet Data on the Incidence of Infection with Pathogens Transmitted Commonly Through Food --- 10 Sites, United States, 2004. MMWR Morb Mortal Wkly Rep. 54(14): 352-356, 2005. Centers for Disease Control and Prevention (CDC). Preliminary FoodNet Data on the Incidence of Infection with Pathogens Transmitted Commonly Through Food --- 10 Sites, United States, 2005. MMWR Morb Mortal Wkly Rep. 54(14): 392-395, 2006. Centers for Disease Control and Prevention (CDC). Ongoing multistate outbreak of Escherichia coli serotype O157:H7 infections associated with consumption of fresh spinach--United States, September 2006. MMWR Morb.Mortal.Wkly.Rep. 55(38): 1045-1046, 2006. Centers for Disease Control and Prevention (CDC). Preliminary FoodNet Data on the Incidence of Infection with Pathogens Transmitted Commonly Through Food - 10 Sites, United States, 2006. MMWR Morb Mortal Wkly Rep. 54(14): 336-339, 2007. Chang CC, Lin YH, Chang CF, Yeh KS, Chiu CH, Chu C, Chien MS, Hsu YM, Tsai LS and Chiou CS. Epidemiologic Relationship between Fluoroquinolone-Resistant Salmonella enterica Serovar Choleraesuis Strains Isolated from Humans and Pigs in Taiwan (1997 to 2002). J Clin Microbiol. 43(6): 2798-2804, 2005. Chen H, Fraser AD and Yamazaki H. Evaluation of the toxicity of Salmonella selective media for shortening the enrichment period. Int.J.Food Microbiol. 18(2): 151-159, 1993. Chen, Y. H., T. P. Chen, J. J. Tsai, K. P. Hwang, P. L. Lu, H. H. Cheng, and C. F. Peng. Epidemiological study of human salmonellosis during 1991-1996 in southern Taiwan. Kaohsiung J. Med. Sci. 15: 127-136, 1999. Chiou CS, Hsu SY, Chiu SI, Wang TK and Chao CS. Vibrio parahaemolyticus Serovar O3:K6 as Cause of Unusually High Incidence of Food-Borne Disease Outbreaks in Taiwan from 1996 to 1999. J Clin Microbiol. 38(12): 4621-4625, 2000. Chiou CS, Huang JF, Tsai LH, Hsu KM, Liao CS and Chang HL. A simple and low-cost paper-bridged method for Salmonella phase reversal. Diagn Microbiol Infect Dis. 54(4): 315-317, 2006. Chiu CH, Chuang CH, Chiu S, Su LH and Lin TY. Salmonella enterica Serotype Choleraesuis Infections in Pediatric Patients. J Microbiol Immunol Infect. 37(2): 99-102, 2006. Chiu CH, Lin TY and Ou JT. Prevalence of the virulence plasmids of nontyphoid Salmonella in the serovars isolated from humans and their association with bacteremia. Microbiol Immunol 43(9): 899-903, 1999. Chiu CH, Su LH and Chu C. Salmonella enterica serotype Choleraesuis: epidemiology, pathogenesis, clinical disease, and treatment. Clin Microbiol Rev.17(2): 311-322, 2004. Chiu CH, Wu TL, Su LH, Chu C, Chia JH, Kuo AJ, Chien MS and Lin TY. The emergence in Taiwan of fluoroquinolone resistance in Salmonella enterica serotype choleraesuis. N Engl J Med. 346(6): 413-419, 2002. Chiu CH, Wu TL, Su LH, Liu JW and Chu C. Fluoroquinolone Resistance in Salmonella enterica Serotype Choleraesuis, Taiwan, 2000-2003. Emerg Infect Dis. 10(9): 1674-1676, 2004. Chiu S, Chiu CH and Lin TY. Salmonella enterica serotype Choleraesuis infection in a Medical center in northern Taiwan. J Microbiol Immunol Infect. 37: 99-102, 2004. Cooke VM, Miles RJ, Price RG and Richardson AC. A Novel Chromogenic Ester Agar Medium for Detection of Salmonellae. Appl Environ Microbiol. 65(2): 807-812, 1999. Corrente M, Madio A, Friedrich KG, Greco G, Desario C, Tagliabue S, D''Incau M, Campolo M and Buonavoglia C. Isolation of Salmonella strains from reptile faeces and comparison of different culture media. J Appl Microbiol. 96(4): 709-715, 2004. Dalton CB, Gregory J, Kirk MD, Stafford RJ, Givney R, Kraa E and Gould D. Foodborne disease outbreaks in Australia, 1995 to 2000. Commun Dis Intell. 28(2): 211-224, 2004. Davies PR, Morrow WE, Jones FT, Deen J, Fedorka-Cray PJ and Harris IT. Prevalence of salmonella in finishing swine raised in different production systems in North Carolina, USA. Epidemiol Infect. 119(2): 237-244, 1997. Davies PR, Turkson PK, Funk JA, Nichols MA, Ladely SR and Fedorka-Cray PJ. Comparison of methods for isolating Salmonella bacteria from faeces of naturally infected pigs. J Appl Microbiol. 89(1): 169-177, 2000. Deb M and Kapoor L. Salmonella nomenclature seen in the literature. Indian J Med Microbiol. 23(3): 204-205, 2005. Difco Laboratories. Culture Media, Prepared . The Difco Manual, Difco Laboratories, Maryland, USA. pp. 564-567, 1998. Duffy EA, Belk KE, Sofos JN, Bellinger GR, Pape A and Smith GC. Extent of microbial contamination in United States pork retail products. J Food Prot. 64(1): 172-178, 2001. Edrington TS, Hume ME, Looper ML, Schultz CL, Fitzgerald AC, Callaway TR, Genovese KJ, Bischoff KM, McReynolds JL, Anderson RC and Nisbet DJ. Variation in the faecal shedding of Salmonella and E. coli O157:H7 in lactating dairy cattle and the examination of Salmonella genotypes using pulse-field gel electrophoresis. Lett. Appl. Microbiol. 38(5): 366-372, 2004. Escartin Ef, Castillo A, Hinojosa-Puga A and Saldana-Lozano J. Prevalence of Salmonella in chorizo and its survival under different storage temperatures. Food Microbiol. 16(5): 479-486, 1999. Escartin EF, Lozano JS, Rodriguez O, Gonzales NM and Torres JA. Incidence and level of Salmonella serovars in raw pork obtained from Mexican butcher shops. Food Microbiol. 12(6): 435-439, 1995. Euzeby JP. Revised Salmonella nomenclature: designation of Salmonella enterica (ex Kauffmann and Edwards 1952) Le Minor and Popoff 1987 sp. nov., nom. rev. as the neotype species of the genus Salmonella Lignieres 1900 (Approved Lists 1980), rejection of the name Salmonella choleraesuis (Smith 1894) Weldin 1927 (Approved Lists 1980), and conservation of the name Salmonella typhi (Schroeter 1886) Warren and Scott 1930 (Approved Lists 1980). Request for an opinion. Int J Syst Bacteriol. 49(2): 927-930, 1999. Feder I, Nietfeld JC, Kelly B, Butine MD, McNamara P and Chengappa MM. Evaluation of enrichment techniques for the isolation of Salmonella choleraesuis from swine feces. J Microbiol Methods. 33(2): 143-151, 1998. Fernandes SA, Tavechio AT, Ghilardi AC, Dias AM, Almeida IA and Melo LC. Salmonella serovars isolated from humans in Sao Paulo State, Brazil, 1996-2003. Rev Inst Med Trop Sao Paulo. 48(4): 179-184, 2006. Fries R and Steinhof U. Growth kinetics of Salmonella in mixed cultures incubated in Rappaport-Vassiliadis medium. Food Microbiol. 14(5): 505-513, 1997. Galbraith N S. Studies of human salmonellosis in relation to infection in animals. Vet Rec. 2(73): 1296-1303, 1961. Garcia Fontan MC, Lorenzo JM, Parada A, Franco I and Carballo J. Microbiological characteristics of ‘‘androlla’’, a Spanish traditional pork sausage. Food Microbiol. 24(1): 52-58, 2007. Giovannini A, Prencipe V, Conte V, Marino L, Petrini A, Pomilio F, Rizzi V and Migliorati G. Quantitative risk assessment of Salmonella spp. infection for the consumer of pork products in an Italian region. Food Control. 15:(2): 139-144, 2004. Gouws PA, Visser M and Brozel VS. A Polymerase Chain Reaction procedure for the detection of Salmonella spp. within 24 h. J Food Prot. 61(8): 1039-1042, 1998. Gray JT and Fedorka-Cray PJ. Survival and Infectivity of Salmonella Choleraesuis in Swine Feces. J Food Prot. 64(7): 945-949, 2001. Gray JT, Fedorka-Cray PJ, Stabel TJ and Kramer TT. Natural Transmission of Salmonella choleraesuis in Swine. Appl Environ Microbiol. 62(1): 141-146, 1996. Guo X, Chen J, Brackett RE and Beuchat LR. Survival of Salmonellae on and in Tomato Plants from the Time of Inoculation at Flowering and Early Stages of Fruit Development through Fruit Ripening. Appl Environ Microbiol. 67(10): 4760-4764, 2001. Honish L and Nquyen Q. Outbreak of Salmonella enteritidis phage type 913 gastroenteritis associated with mung bean sprouts--Edmonton, 2001. Can Commun Dis Rep. 27(18): 151-156, 2001. Hoorfar J and Baggesen DL. Importance of pre-enrichment media for isolation of Salmonella spp. from swine and poultry. FEMS Microbiol.Lett. 169(1): 125-130, 1998. Hopkins KL and Threlfall EJ. Frequency and polymorphism of sopE in isolates of Salmonella enterica belonging to the ten most prevalent serotypes in England and Wales. J Med Microbiol. 53(6): 539-543, 2004. Hsueh PR, Teng LJ, Tseng SP, Chang CF, Wan JH, Yan JJ, Lee CM, Chuang YC, Huang WK, Yang D, Shyr JM, Yu KW, Wang LS, Lu JJ, Ko WC, Wu JJ, Chang FY, Yang YC, Lau YJ, Liu YC, Liu CY, Ho SW and Luh KT. ciprofloxacin-resistant Salmonella enterica Typhimurium and Choleraesuis from Pigs to Humans, Taiwan. Emerg Infect Dis. 10(1): 60-68, 2004. Islam M, Morgan J, Doyle MP, Phatak SC, Millner P and Jiang X. Fate of Salmonella enterica Serovar Typhimurium on Carrots and Radishes Grown in Fields Treated with Contaminated Manure Composts or Irrigation Water.Appl Environ Microbiol. 70(4): 2497-2502, 2004. Jean SS, Wang JY and Hsueh PR. Bacteremia caused by Salmonella enterica serotype Choleraesuis in Taiwan. J Microbiol Immunol Infect. 39(5): 358-365, 2006. Johannessen GS, Froseth RB, Solemdal L, Jarp J;Wasteson Y and Rorvik LM. Influence of bovine manure as fertilizer on the bacteriological quality of organic Iceberg lettuce. J Appl Microbiol. 96(4): 787-794, 2004. Khakhria R, Woodward D, Johnson WM and Poppe C. Salmonella isolated from humans, animals and other sources in Canada, 1983-92. Epidemiol Infect. 119(1): 15-23, 1997. Kimura AC, Reddy V, Marcus R, Cieslak PR, Mohle-Boetani JC, Kassenborg HD, Segler SD, Hardnett FP, Barrett T and Swerdlow DL. Chicken consumption is a newly identified risk factor for sporadic Salmonella enterica serotype Enteritidis infections in the United States: a case-control study in FoodNet sites. Clin Infect Dis. 38(3): 244-252, 2004. Krause G, Terzagian R and Hammond R. Outbreak of Salmonella serotype Anatum infection associated with unpasteurized orange juice. South Med J. 94(12): 1168-1172, 2002. Lemunier M, Francou C, Rousseaux S, Houot S, Dantigny P, Piveteau P and Guzzo J. Long-Term Survival of Pathogenic and Sanitation Indicator Bacteria in Experimental Biowaste Composts. Appl Environ Microbiol. 71(10): 5779-5786, 2005. Letellier A, Messier S, Pare J, Menard J and Quessy S. Distribution of Salmonella in swine herds in Quebec. Vet Microbiol. 67(4): 299-306, 1999. Maguire HC, Codd AA, Mackay VE, Rowe B and Mitchell E. A large outbreak of human salmonellosis traced to a local pig farm. Epidemiol Infect. 10(2): 239-246, 1993. Malorny B and Hoorfar J. Toward Standardization of Diagnostic PCR Testing of Fecal Samples: Lessons from the Detection of Salmonellae in Pigs. J Clin Microbiol. 43(7): 3033-3037, 2005. McDonald LC, Chen MT, Lauderdale TL and Ho M. The use of antibiotics critical to human medicine in food-producing animals in Taiwan. J Microbiol Immunol Infect. 34(2): 97-102, 2001. Mead PS, Slutsker L, Dietz V, McCaig LF, Bresee JS, Shapiro C, Griffin PM and Tauxe RV. Food-related illness and death in the United States. Emerg Infect Dis. 5(5): 607-625, 1999. Mejia W, Casal J, Zapata D, Sanchez G.J, Martin M and Mateu E. Epidemiology of salmonella infections in pig units and antimicrobial susceptibility profiles of the strains of Salmonella species isolated. Vet Rec. 159(9): 271-276, 2006. Mitchell MA and Shane SM. Preliminary findings of Salmonella spp. in captive green iguanas (Iguana iguana) and their environment. Prev Vet Med. 45(3): 297-304, 2000. Myint MS, Johnson YJ, Tablante NL and Heckert RA. The effect of pre-enrichment protocol on the sensitivity and specificity of PCR for detection of naturally contaminated Salmonella in raw poultry compared to conventional culture. Food Microbiol. 23(6): 599-604, 2006. National Disease Surveillance Centre. Annual report 2001. St. Patrick Dun’s Hospital, Dublin, Ireland. [Online.] http://www.ndsc.ie. Nnalue NA, Shnyra A, Hultenby K and Lindberg AA. Salmonella choleraesuis and Salmonella typhimurium Associated with Liver Cells after Intravenous Inoculation of Rats Are Localized Mainly in Kupffer Cells and Multiply Intracellularly. Infect Immun. 60(7): 2758-2768, 1992. Oliveira CJ, Carvalho LF and Garcia TB. Experimental airborne transmission of Salmonella Agona and Salmonella Typhimurium in weaned pigs. Epidemiol Infect. 134(1): 199-209, 2006. Olsen SJ, Bishop R, Brenner FW, Roels TH, Bean N, Tauxe RV and Slutsker L.The changing epidemiology of Salmonella: trends in serotypes isolated from humans in the United States, 1987-1997. J Infect Dis. 183(5): 753-761, 2001. O''Reilly CE, Bowen AB, Perez NE, Sarisky JP, Shepherd CA, Miller MD, Hubbard BC, Herring M, Buchanan SD, Fitzgerald CC, Hill V, Arrowood MJ, Xiao LX, Hoekstra RM, Mintz ED and Lynch MF. A Waterborne Outbreak of Gastroenteritis with Multiple Etiologies among Resort Island Visitors and Residents: Ohio, 2004. Clin Infect Dis. 44(4): 506-512, 2004. Orji MU, Onuigbo HC and Mbata TI. Isolation of Salmonella from poultry droppings and other environmental sources in Awka, Nigeria. Int J Infect Dis. 9(2): 86-89, 2005. Pan TM, Wang TK, Lee CL, Chien SW and Horng CB. Food-Borne Disease Outbreaks Due to Bacteria in Taiwan, 1986 to 1995. J Clin Microbiol. 35(5): 1260-1262, 1997. Peutherer JF, Greenwood D and Slack RCB. Salmonella. Medical microbiology :a guide to microbial infections : pathogenesis, immunity, laboratory diagnosis, and control, Churchill Livingstone, Edinburgh, UK. pp.250-259, 2002. Popoff MY, Bockemuhl J and Brenner FW. Supplement 2002 (no. 46) to the Kauffmann-White scheme. Res Microbiol. 151(1): 568-570, 2004. Pundsack JW, Hicks RE and Axler RP. Effect of alternative on-site wastewater treatment on the viability and culturability of Salmonella choleraesuis. J Water Health. 3(1): 1-14, 2005. Quinn PJ, Markey BK, Carter ME, Donnelly WJ and Leonard F. Enterobacteriaceae. Veterinary microbiology and microbial disease, Blackwell Science, Oxford, UK. pp.106-123, 2002. Rabsch W, Tschape H and Baumler AJ. Non-typhoidal salmonellosis: emerging problems. Microbes Infect.3(3): 237-247, 2001. Read SC, Irwin RJ, Poppe C and Harris J. A comparison of two methods for isolation of Salmonella from poultry litter samples. Poult Sci. 73(10): 1617-21, 1994. Reeves MW, Evins GM, Heiba AA, Plikaytis BD and Farmer JJ. Clonal nature of Salmonella typhi and its genetic relatedness to other salmonellae as shown by multilocus enzyme electrophoresis, and proposal of Salmonella bongori comb. nov. J Clin Microbiol. 27(2): 313-320, 1989. Ruiz Gomez J, Lorente Salinas I, Perez Salmeron J, Simarro Cordoba E and Martinez Campos L. Evaluation of methods for isolation of Salmonella species using modified semisolid Rappaport-Vassiliadis medium and Salmonella -Shigella agar. Eur J Clin Microbiol Infect Dis. 17(11): 791-793, 1998. Ruiz J, Nunez ML, Diaz J, Lorente I, Perez J and Gomez J. Comparison of Five Plating Media for Isolation of Salmonella Species from Human Stools. J Clin Microbiol. 34(3): 686-688, 1996a. Ruiz J, Nunez ML, Lorente I, Perez J, Simarro E and Gomez J. Performance of six culture media for isolation of Salmonella species from stool samples. Eur J Clin Microbiol Infect Dis. 15(12): 922-926, 1996b. Russ CF and Yanko WA. 1981. Factors affecting Salmonella repopulation in composted sludges. Appl Environ Microbiol. 41(3): 597-602, 1981. Schuster CJ, Ellis AG, Robertson WJ, Charron DF, Aramini JJ, Marshall BJ and Medeiros DT. Infectious disease outbreaks related to drinking water in Canada , 1974-2001.Can J Public Health. 94(4): 254-58, 2005. Su HP, Chiu SI, Tsai JL, Lee CL and Pan TM. Bacterial food-borne illness outbreaks in northern Taiwan, 1995-2001. J.Infect Chemother. 11(3): 146-151, 2005. Tindall BJ, Grimont PA, Garrity GM and Euzeby JP. Nomenclature and taxonomy of the genus Salmonella. Int J Syst Evol Microbiol. 55(1):521-524, 2005. Tran TP, Ly TL, Nguyen TT, Akiba M, Ogasawara N, Shinoda D, Okatani TA and Hayashidani H. Prevalence of Salmonella spp. in Pigs, Chickens and Ducks in the Mekong Delta,Vietnam. J Vet Med Sci. 66(8): 1011-1014, 2004. Turner,C. The thermal inactivation of E. coli in straw and pig manure. Bioresour Technol. 84(1): 57-61, 2002. Uzzau S, Brown DJ, Wallis T, Rubino S, Leori G, Bernard S, Casadesus J, Platt DJ and Olsen JE. Host adapted serotypes of Salmonella enterica. Epidemiol Infect. 125(2): 229-255, 2000. Valdezate S, Vidal A, Herrera-Leon S, Pozo J, Rubio P, Usera MA, Carvajal A and Echeita MA. Salmonella Derby Clonal Spread from Pork. Emerg Infect Dis.11(5): 694-698, 2005. Voogt N, Raes M, Wannet WJ, Henken AM and van de Giessen AW. Comparison of selective enrichment media for the detection of Salmonella in poultry faeces. Lett Appl Microbiol. 32(2): 89-92, 2001. Wang JY, Hwang JJ, Hsu CN, Lin LC and Hsueh PR. Bacteraemia due to ciprofloxacin-resistant Salmonella enterica serotype Choleraesuis in adult patients at a university hospital in Taiwan, 1996-2004. Epidemiol Infect. 134(5): 977-984, 2006. Watabe M, Rao JR, Stewart TA, Xu J, Millar BC, Xiao L, Lowery CJ, Dooley JSG and Moore JE. Prevalence of bacterial faecal pathogens in separated and unseparated stored pig slurry. Lett. Appl. Microbiol. 36(4) :208-212, 2003. Werber D, Dreesman J, Feil F, Treeck Uv, Fell G, Ethelberg S, Hauri AM, Roggentin P, Prager R, Fisher IS, Behnke SC, Bartelt E, Weise E, Ellis A, Siitonen A, Andersson Y, Tschape H, Kramer MH and Ammon A. International outbreak of Salmonella Oranienburg due to German chocolate. BMC Infect Dis. 5(1): 7, 2005. White PL, Baker AR and James WO. Strategies to control Salmonella and Campylobacter in raw poultry products. Rev Sci Tech. 16(2): 525-541, 1997. Wiley BB and Westerberg SC. Survival of Human Pathogens in Composted Sewage. Appl.Microbiol. 18(6): 994-1001, 1969. Wood RL, Pospischil A and RoseR. Distribution of persistent Salmonella typhimurium infection in internal organs of swine. Am J Vet Res. 50(7): 1015-1021, 1989. Wray C. and Wray A.Taxonomy of the Genus Salmonella. Salmonella in domestic animals, CABI, Oxon, UK. pp.1-17, 2000. Yan SS, Pendark ML, Abela-Ridder B, Punderson JW, Fedorko DP and Foley SL. An overview of Salmonella typing Public health perspectives. Applied Immunol Rev. 4(3): 189-204, 2003. Younus M, Wilkins MJ, Arshad MM, Rahbar MH and Saeed AM. Demographic Risk Factors and Incidence of Salmonella Enteritidis Infection in Michigan. Foodborne Pathog Dis. 3(3): 266-273, 2006. Zdragas A, Tsakos P and Mavrogeni P. Evaluation of two assays, MSRV and RV, for the isolation of Salmonella spp. from wastewater samples and broiler chickens. Lett Appl Microbiol. 31(4): 328-331, 2000. Zhao C, Ge B, De Villena J, Sudler R, Yeh E, Zhao S, White DG, Wagner D and Meng J. Prevalence of Campylobacter spp., Escherichia coli, and Salmonella Serovars in Retail Chicken, Turkey, Pork, and Beef from the Greater Washington, D.C., Area. Appl Envir Microbiol. 67(12): 5431-5436, 2001. 邱乾順,陳裴珊,蕭淑君,黃靜芳,林怡璇,廖春杏,蔡麗淑,李俊青,廖璿程,賴麗娟。2004 年台灣沙門氏菌血清型與基因型。第一屆沙門氏菌研討會 p6。
摘要: 沙門氏菌症 (Salmonellosis) 爲一全球性之重要人畜共通傳染病。美國每年約有140萬人感染非傷寒沙門氏菌症並造成近600名死亡案例。台灣方面以Salmonella Typhimurium、S. Enteritidis、S. Stanley、S. Agona、S. Albany、S. Schwarzengrund、S. Newport、S. Choleraesuis、S. Derby及 S. Weltevreden等為人類常見感染的血清型。台灣的人類豬霍亂沙門氏菌症為全球相當獨特的地方性疾病,人類受豬霍亂沙門氏菌 (S. Choleraesuis) 感染通常會引發全身性的感染如菌血症,嚴重時甚至會導致病人死亡。本研究藉由調查環境當中沙門氏菌之分佈情形並對患病個案進行問卷的回溯性訪視調查,以取得沙門氏菌患者發病前的流行病學資料,藉此瞭解台灣人類沙門氏菌症之感染來源、相關危險因子及找出台灣人類感染豬霍亂沙門氏菌的相關危險因子。總計952個採檢樣本結果顯示,超市和傳統市場的豬肝沙門氏菌陽性檢出率分別為41.8 % (28/67) 和39.3 % (22/56);豬場糞便的沙門氏菌陽性率為48.6 % (53/109),其中也發現 S. Derby (17.2 %)、S. Agona (10.3 %) 和 S. Albany (8.3 %) 等台灣人類沙門氏菌病患常見之血清型別;堆肥場半成品 (未完成發酵) 及成品 (完成發酵) 堆肥之沙門氏菌陽性率分別為6.1 % (22/360) 和3.1 % (11/360),進一步分析季節因素造成之影響,顯示夏季時堆肥場半成品陽性檢出率顯著高於冬天 (p < 0.05)。然而,由環境中所取得之樣本皆無 S. Choleraesuis 之發現。在回溯性研究調查單因子變項分析結果顯示,吃雞蛋為台灣地區民眾感染血清型S. Enteritidis的危險因子。利用病例對照研究的多變項分析結果,指出飲用地下水及年齡70歲以上 (含) 等二因子為台灣人類感染豬霍亂沙門氏菌的重要危險因子。以上的研究資訊將有助於發展沙門氏菌的防治策略,以減低人類感染疾病的風險。
Salmonellosis is an important zoonosis worldwide. It was estimated that 1.4 million human cases with non-typhoidal Salmonella infections, and probably 600 related deaths occur in the United States annually. In Taiwan, the majority of human Salmonella cases are caused by serotypes of Salmonella Typhimurium, S. Enteritidis, S. Stanley, S. Agona, S. Albany, S. Schwarzengrund, S. Newport, S. Choleraesuis, S. Derby and S. Weltevreden. However, the infection of S. Choleraesuis in humans can be considered as an endemic disease in Taiwan, as compared to the situation in the other countries. In humans, S. Choleraesuis infection ofen causes systemic infection such as bacteremia, which might eventually lead to death. Therefore, through environmental investigation and retrospective studies, the objectives of this study were: 1) to determine the distribution of Salmonella spp. in environment; 2) to identifty the associated risk factors of Salmonella infection in humans and; 3) to understand the sources of Salmonella infection in humans. A total of 952 samples collected from various sources were used for isolation of Salmonella. None of the environmental samples were S. Choleraesuis positive. However, Salmonella spp. were isolated from 39.3 % (22/65) and 41.8 % (28/67) of porcine liver collected from traditional markets and supermarkets, respectively. The percentage of Salmonella-positive pig excreta collected from pig farms was determined to be 48.6 % (53/109). Furthermore, S. Derby (17.2 %), S. Agona (10.3 %) and S. Albany (8.3 %), which were commonly seen in human salmonellosis in Taiwan, were found in the pig excreta. For the specimens collected from certified compost factories, Salmonella could still be isolated from 6.1 % (22/360) of semi- processed products and 3.1 % (11/360) of finished products. Further stratified by different seasons for semi-processed products, a significantly higher percentage of Salmonella-positive specimens was identified in summer than in winter (p < 0.05). As for the case-cortrol studie of S. Enteritidis, univariate analysis showed that history of egg intake was a significant risk factor in humans in Taiwan. However, multiunivariate analysis on the basis of the case-controly study of S. Choleraesuis in humans indicated that drinking underground water and patients older than 70 year-old were two significant risk factors for S. Choleraesuis infection. The above information will be helpful for the development of effective strategies for prevention and to reduce the risk of human Salmonella infection in Taiwan.
URI: http://hdl.handle.net/11455/66336
其他識別: U0005-1007200715474800
文章連結: http://www.airitilibrary.com/Publication/alDetailedMesh1?DocID=U0005-1007200715474800
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