Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/69344
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dc.contributor.authorHsu, S.C.en_US
dc.contributor.authorChiu, T.H.en_US
dc.contributor.authorPang, J.C.en_US
dc.contributor.authorHsuan-Yuan, C.H.en_US
dc.contributor.authorChang, G.N.en_US
dc.contributor.authorTsen, H.Y.en_US
dc.date2006zh_TW
dc.date.accessioned2014-06-11T05:58:11Z-
dc.date.available2014-06-11T05:58:11Z-
dc.identifier.issn0924-8579zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/69344-
dc.description.abstractEscherichia coli isolates from humans (n = 110) and swine (n = 61) and Salmonella enterica serovar Choleraesuis isolates (n = 95) from swine in southern Taiwan were characterised for antimicrobial resistance patterns and class 1 integrons. All E. coli isolates and S. Choleraesuis isolates were multidrug resistant and demonstrated high resistance to beta-lactams, aminoglycosides, tetracycline, sulfonamides, spectinomycin, chloramphenicol and nalidixic acid. By polymerase chain reaction and DNA sequencing, 104 (61%) E. coli isolates and 31 (33%) S. Choleraesuis isolates were found to carry class 1 integrons. The gene cassette array dfrA12-orfF-aadA2 was the most prevalent (24%) among the human and swine E. coli isolates, whilst the gene cassette array dfrA12-orfF-aadA2-sull was the most prevalent (24%) among S. Choleraesuis strains. For E. coil isolates, all class 1 integrons were located on conjugated plasmids. Meanwhile, human and swine E. coli isolates carrying identical gene cassettes were genetically unrelated. Our results revealed that multidrug resistance and class I integrons were widely present in E. coli and S. Choleraesuis isolates obtained in Taiwan and that class 1 integrons might play an important role in contributing to the horizontal transfer of antimicrobial resistance. (c) 2006 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.en_US
dc.language.isoen_USzh_TW
dc.relationInternational Journal of Antimicrobial Agentsen_US
dc.relation.ispartofseriesInternational Journal of Antimicrobial Agents, Volume 27, Issue 5, Page(s) 383-391.en_US
dc.relation.urihttp://dx.doi.org/10.1016/j.ijantimicag.2005.11.020en_US
dc.subjectantibiotic-resistanceen_US
dc.subjectgene cassettesen_US
dc.subjectdrug-resistanceen_US
dc.subjectfood animalsen_US
dc.subjectpcr primersen_US
dc.subjectenterobacteriaceaeen_US
dc.subjectphenotypesen_US
dc.subjecthospitalsen_US
dc.subjectbacteriaen_US
dc.subjectsamplesen_US
dc.titleCharacterisation of antimicrobial resistance patterns and class I integrons among Escherichia coli and Salmonella enterica serovar Choleraesuis strains isolated from humans and swine in Taiwanen_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1016/j.ijantimicag.2005.11.020zh_TW
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