Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/69604
標題: A 10-year Follow-up of Triple-negative Breast Cancer Patients in Taiwan
作者: Lin, C.
Chien, S.Y.
Kuo, S.J.
Chen, L.S.
Chen, S.T.
Lai, H.W.
Chang, T.W.
Chen, D.R.
關鍵字: triple-negative breast cancer
HER2
estrogen receptor
progesterone
receptor
survival
international expert consensus
long-term survival
estrogen-receptor
prognostic-factor
primary therapy
carcinoma
subtype
metastasis
highlights
recurrence
期刊/報告no:: Japanese Journal of Clinical Oncology, Volume 42, Issue 3, Page(s) 161-167.
摘要: This study aimed to investigate whether triple-negative breast cancer has a worse prognosis; here, we present the 10-year follow-up results of triple-negative breast cancer patients in Taiwan. We identified 2858 breast cancer patients in Taiwan, of whom 416 (14.6) had triple-negative breast cancer. Data used for analysis were derived from those breast cancer patients who were diagnosed between January 1996 and December 2006. In the KaplanMeier analysis, tumor subgroup (triple-negative breast cancer vs. non-triple-negative breast cancer) was a prognostic factor related to 10-year breast cancer death-specific survival and disease-free survival. The results of univariate analysis showed that tumor subgroup was a significant factor related to 10-year disease-free survival and breast cancer death-specific survival, as well as menopausal status, tumor size, lymph node, metastasis, grade, stage, estrogen receptor status, progesterone receptor status and her2/neu gene expression status. Similarly, the multivariate analysis also revealed that tumor subgroup was a significant factor related to 10-year breast cancer death-specific survival and disease-free survival, in addition to tumor size, lymph node, metastasis and grade. It was suggested that triple-negative breast cancer patients in Taiwan have worse 10-year survival. Notably, in node-positive patients, triple-negative breast cancer played a prognostic role in 10-year breast cancer death-specific survival.
URI: http://hdl.handle.net/11455/69604
ISSN: 0368-2811
文章連結: http://dx.doi.org/10.1093/jjco/hyr196
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