請用此 Handle URI 來引用此文件: http://hdl.handle.net/11455/69770
標題: Exploration of the Relationship Between the Tumor Burden and the Concentration of Vascular Endothelial Growth Factor in Liver-Cancer-Bearing Animals Using Immunomagnetic Reduction Assay
作者: Huang, K.W.
Yang, S.Y.
Yu, C.Y.
Chieh, J.J.
Yang, C.C.
Horng, H.E.
Hong, C.Y.
Yang, H.C.
Wu, C.C.
關鍵字: Immunomagnetic Reduction
Vascular Endothelial Growth Factor
Magnetic
Nanoparticle
Hepatocellular Carcinoma
Animal Model
human hepatocellular-carcinoma
magnetic nanoparticles
factor vegf
marker
expression
virus
期刊/報告no:: Journal of Biomedical Nanotechnology, Volume 7, Issue 4, Page(s) 535-541.
摘要: To achieve early-stage diagnosis, a high-sensitivity assay method is needed. As a biomarker, vascular endothelial growth factor (VEGF) has played a growing role in diagnosing and treating hepatocellular carcinoma (HCC). In this work, an immunomagnetic reduction (IMR) through bio-functionalized magnetic nanoparticles and a high-temperature superconducting-quantum-interference-device magnetometer were utilized for quantitative detection of low-concentration VEGF in serum from rats with HCC. The precision and accuracy of IMR on VEGF were characterized. Further, the results of assaying VEGF in the serum of rats were compared with those of using enzyme-linked immunosorbant assay (ELISA). It was found the correlations between the detected VEGF concentration in the rat serum and tumor burdens were 0.99 and 0.90 for IMR and ELISA, respectively, within the range from 2 pg/ml to 8000 pg/ml of VEGF concentration.
URI: http://hdl.handle.net/11455/69770
ISSN: 1550-7033
文章連結: http://dx.doi.org/10.1166/jbn.2011.1321
顯示於類別:期刊論文

文件中的檔案:
沒有與此文件相關的檔案。


在 DSpace 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。