Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/69903
標題: In Vitro Bioactivity and Biocompatibility of Dicalcium Silicate Cements for Endodontic Use
作者: Chen, C.C.
Ho, C.C.
Chen, C.H.D.
Wang, W.C.
Ding, S.J.
關鍵字: Bioactivity
biocompatibility
calcium silicate cement
endodontics
mineral trioxide aggregate
mineral trioxide aggregate
phosphate-containing fluid
white
portland-cement
calcium
期刊/報告no:: Journal of Endodontics, Volume 35, Issue 11, Page(s) 1554-1557.
摘要: Introduction: The purpose of this study was to examine the in vitro bioactivity and biocompatibility of sol-gel-derived dicalcium silicate cements. Methods: The morphology, phase composition, and compressive strength of the novel cement were investigated after immersion in a simulated body fluid for different periods of time. Cement biocompatibility was evaluated by incubating the cement specimens with MG63 human osteoblast-like cells. Results: After immersion in a simulated body fluid as little as 1 hour, the cements were covered with clusters of bone-like apatite spherulites. The characteristic peaks of apatite at 2 theta = 25.9 degrees and 31.8 - 32.9 degrees appeared. The compressive strength of the cement was increased from the initial strength value of 12.3 MPa to 1-day strength value of 20.2 MPa; these values were significantly different (P < .05). The MG63 cell viability increased 15% and 23% on the cement surfaces when compared with the control on hour 6 and day 7 of incubation, respectively. The cells appeared flat and exhibited intact, well-defined morphology on the cement surface. Conclusions: Both bioactivity and biocompatibility of the dicalcium silicate cement consistently make it a potential candidate for endodontic use. (J Endod 2009,35:1554-1557)
URI: http://hdl.handle.net/11455/69903
ISSN: 0099-2399
文章連結: http://dx.doi.org/10.1016/j.joen.2009.08.006
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