請用此 Handle URI 來引用此文件: http://hdl.handle.net/11455/85002
標題: Synthesis of Hydroxylated Analogues of α-Galactosyl Ceramide (KRN7000)with Varying Stereochemistry
關鍵字: Carbohydrates
Glycolipids
Sphingolipids
Cerebrosides
Structure–activity relationships
摘要: The synthesis of analogues of α-galactosyl ceramide (KRN7000) with an additional hydroxy group in the phytosphingosine chains and with varying stereochemistry is described. Careful selection of glucose, galactose, mannose, and talose hexopyranoses allowed us to control the stereochemistry of some of the hydroxy groups in the sphingosine chain to give some interesting hydroxylated KRN7000 analogues.
URI: http://hdl.handle.net/11455/85002
文章連結: http://onlinelibrary.wiley.com/doi/10.1002/ejoc.201301111/abstract
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