Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/86354
標題: Metal nanobullets for multidrug resistant bacteria and biofilms
作者: Chen, Ching-Wen
Hsu, Chia-Yen
Lai, Syu-Ming
Syu, Wei-Jhe
Wang, Ting-Yi
Lai, Ping-Shan
關鍵字: Antibacterial
Biofilm
Drug resistance
Metallic nanoparticles
Toxicology
Animals
Anti-Bacterial Agents
Bacterial Infections
Biofilms
Drug Design
Drug Resistance, Multiple, Bacterial
Humans
Metal Nanoparticles
摘要: Infectious diseases were one of the major causes of mortality until now because drug-resistant bacteria have arisen under broad use and abuse of antibacterial drugs. These multidrug-resistant bacteria pose a major challenge to the effective control of bacterial infections and this threat has prompted the development of alternative strategies to treat bacterial diseases. Recently, use of metallic nanoparticles (NPs) as antibacterial agents is one of the promising strategies against bacterial drug resistance. This review first describes mechanisms of bacterial drug resistance and then focuses on the properties and applications of metallic NPs as antibiotic agents to deal with antibiotic-sensitive and -resistant bacteria. We also provide an overview of metallic NPs as bactericidal agents combating antibiotic-resistant bacteria and their potential in vivo toxicology for further drug development.
URI: http://hdl.handle.net/11455/86354
ISSN: 0169409X
1872-8294
Appears in Collections:化學系所

文件中的檔案:

取得全文請前往華藝線上圖書館



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.