Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/94638
標題: The Feasibility of Thermophilic Caldimonas manganoxidans as a Platform for Efficient PHB Production
作者: Hsiao, Li-Jung
Lin, Ji-Hong
Sankatumvong, Pantitra
Wu, Tzong-Ming
Li, Si-Yu
李思禹
關鍵字: Caldimonas manganoxidans
Glucose
Molecular weight
Poly(3-hydroxybutyrate) (PHB)
Substrate inhibition
Thermophiles
Biomass
Carbon
Comamonadaceae
Feasibility Studies
Glucose
Hydrogen-Ion Concentration
Hydroxybutyrates
Molecular Weight
Nitrogen
Oxygen
Polyesters
Spectroscopy, Fourier Transform Infrared
Time Factors
Temperature
摘要: Recently, poly(3-hydroxybutyrate) (PHB) has been found in a few thermophilic strains where several advantages can be gained from running fermentation at high temperatures. Caldimonas manganoxidans, a thermophilic gram-negative bacterium, was investigated for the feasibility as a PHB-producing strain. It is suggested that the best fermentation strategy for achieving the highest PHB concentration of 5.4 ± 1.1 g/L (from 20 g/L glucose) in 24 h is to use the fermentation conditions that are favored for the bacterial growth, yet temperature and pH should be chosen at conditions that are favored for the PHB content. Besides, the above fermentation conditions produce PHB that has a high molecular weight of 1274 kDa with a low polydispersity index (PDI) of 1.45, where the highest Mw of PHB of 1399 kDa (PDI of 1.32) is obtained in this study. To the best knowledge of authors, C. manganoxidans has the best PHB productivity among the thermophiles and is comparable to those common PHB-producing mesophiles.
URI: http://hdl.handle.net/11455/94638
Appears in Collections:化學工程學系所

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