請用此 Handle URI 來引用此文件: http://hdl.handle.net/11455/94826
標題: Antibacterial and laxative activities of strictinin isolated from Pu'er tea (Camellia sinensis)
作者: Hsieh, Sheng-Kuo
Xu, Jun-Rui
Lin, Nan-Hei
Li, Yue-Chiun
Chen, Guan-Heng
Kuo, Ping-Chung
Chen, Wen-Ying
Tzen, Jason T C
關鍵字: Pu'er tea
antibacterial activity
laxative effect
strictinin
Animals
Anti-Bacterial Agents
Laxatives
Phenols
Rats
Tea
Camellia sinensis
摘要: Strictinin, the major phenolic compound in Pu'er teas produced from young leaves and buds of wild trees, was isolated to evaluate its antibacterial and laxative activities. The minimum inhibitory concentrations of strictinin against Propionibacterium acnes and Staphylococcus epidermidis were determined as 250 μM and 2000 μM, respectively, apparently higher than those of several antibiotics commonly used for bacterial infections. The additive and synergistic effects on the inhibitory activities of strictinin combined with other commercial antibiotics were observed in two bacteria tested in this study via the analysis of fractional inhibitory concentrations. Laxative activity was observed on defecation of the rats fed with strictinin. Further analysis showed that the laxative effect of strictinin was presumably caused by accelerating small intestinal transit, instead of enhancing gastric emptying, increasing food intake, or inducing diarrhea in the rats. Taken together with the antiviral activities demonstrated previously, it is suggested that strictinin is one of the active ingredients responsible for the antiviral, antibacterial, and laxative effects of wild Pu'er tea, and has the potential to be developed as a mild natural substitute for antibiotics and laxatives.
URI: http://hdl.handle.net/11455/94826
ISSN: 1021-9498
顯示於類別:獸醫學系所

文件中的檔案:
沒有與此文件相關的檔案。


在 DSpace 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。