Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/97603
標題: 兩性偶氮苯樹枝狀衍生物的合成與可見光驅動順反異構化的探討
Synthesis of visible-light triggerable amphiphilic azobenzene dendrons toward liposome-based drug delivery.
作者: 王吉東
Ji-Dong Wang
關鍵字: 偶氮苯
光控
azobenzene
photoswitch
引用: References 1. Golan, D. E.; Armstrong, E. J.; Armstrong, A. W. Principles of pharmacology: The Pathophysiological Basis of Drug Therapy, 4th ed.; Lippincott Williams&Wilkins: Philadelphia, 2008. 2. Jain, K. K. Drug delivery systems—an overview. Humana: New York, 2008. 3. Bajpai, A. K.; Shukla, S. K.; Bhanu, S. Prog Polym Sci. 2008, 33, 1088-1118. 4. Robinson, J. R.; Lee, V. H. L. Controlled Drug Delivery: Fundamentals and Applications. Dekker: New York, 1987. 5. Bangham, A. D.; Standish, M. M.; Watkins, J. C. J. Mol. Biol. 1965, 13, 238-252. 6. Paasonen, L.; Romberg, B.; Storm, G. Bioconjug Chem. 2007, 18, 2131-2136. 7. Sharma, A.; Sharma, U. S. Int J Pharm. 1997, 154, 123-140. 8. L., Paasonen; B., Romberg; G., Storm; M., Yliperttula; A., Urtti; W. E., Hennick. Bioconjug Chem. 2007, 18, 2131-2136. 9. Betz, G.; Aeppli, A.; Menshutina, N.; Leuenberger, H. Int. J. Pharm. 2005, 296, 44−54. 10. Mu, L.; Sprando, R. L. Pharm. Res. 2010, 27, 1746-1749. 11. Taylor, T. M.; Davidson, P. M.; Bruce, B. D.; Weiss, J. Crit. Rev. Food Sci. Nutr. 2005, 45, 587−605. 12. Mozafari, M. R.; Johnson, C.; Hatziantoniou, S.; Demetzos, C. J. Liposome Res. 2008, 18, 309-327. 13. Mozafari, M. R. Cell Mol Biol Lett. 2005, 10, 711-719. 14. Miranda, D.; Lovell, J. F. Bioeng Transl Med. 2016, 1, 267-276. 15. Leung, S. J.; Romanowski, M. Theranostics. 2012, 2, 1020-1036. 16. Hester, T. J.; Dennison, S. R.; Baker, M. J.; Snape, T. J. Org Biomol Chem. 2015, 13, 8067–8070. 17. Merino, E.; Ribagorda, M. Beilstein J Org Chem. 2012, 8, 1071–1090. 18. Pelliccioli, A. P.; Wirz, J. Photochem Photobiol Sci. 2002, 1, 441–458. 19. Bayer, A. M.; Alam, S.; Mattern-Schain, S. I.; Best, M. D. Chem Eur J. 2014, 20, 3350–3357. 20. Kolb, H. C.; Finn, M. G.; Sharpless, K. B. Angew. Chem., Int. Ed. 2001, 40, 2004–2021. 21. Bock, V. D.; Hiemstra, H.; Maarseveen, J. H-V. Eur. J. Org. Chem. 2006, 1, 51–68. 22. Himo, F.; Lovell, T.; Hilgraf, R.; Rostovtsev, V. V.; Noodleman, L.; Sharpless, K. B.; Fokin, V. V. J. Am. Chem. Soc. 2005, 127, 210–216. 23. Rostovtsev, V. V.; Green, L. G.; Fokin, V. V.; Sharpless, K. B. Angew. Chem., Int. Ed., Engl. 2002, 41, 2596–2599. 24. Worell, B. T.; Malik, J. A.; Fokin, V. V. Science. 2013, 340, 457-460. 25. Immordino, M. L.; Dosio, F.; Cattel, L. Int. J. Nanomed. 2006, 1, 297–315. 26. Merino, Estı´baliz. Chem. Soc. Rev. 2011, 40, 3835–3853. 27. Zhen, W.; Han, H.; Anguiano, M.; Lemere, C.; Cho, C. G.; Lansbury, P. T. J. Med. Chem. 1999, 42, 2805-2815. 28. Haghbeen, K.; Tan, E. W. J. Org. Chem., 1998, 63, 4503-4505. 29. Svele, I.; Zollinger, H. Top. Curr. Chem. 1983, 112, 1-66. 30. Davey, H. H.; Lee, R. D.; Marks, T. J. J. Org. Chem. 1999, 64, 4976-4979. 31. Ueno, K.; Akiyoshi, S. J. Am. Chem. Soc. 1954, 76, 3670-3672. 32. Shimao, I.; Oae, S. Bull. Chem. Soc. Jpn. 1983, 56, 643-644. 33. Shimao, I.; Matsumura, S. Bull. Chem. Soc. Jpn. 1976, 49, 2294-2297. 34. Hartley, G. S. Nature. 1937, 140, 281-281. 35. Dong, M.; Babalhavaeji, A.; Samanta, S.; Beharry, A. A.; Woolley, G. A. Acc. Chem. Res. 2015, 48, 2662-2670. 36. Lesch, J. E. The first miracle drugs: How the sulfa drugs transformed medicine; Oxford University Press: New York, 2007. 37. Thomas, B. H.; Whitehouse, L. W.; Solomonraj, G.; Paul, C. J. J. Pharm. Sci. 1990, 79, 321-325. 38. Brown, M. A.; Devito, S. C. Crit. Rev. Environ. Sci. Technol. 1993, 23, 249-324. 39. Cheong, W. F.; Prahl, S. A.; Welch, A. J. IEEE J. Quantum Electron. 1990, 26, 2166-2185. 40. Beharry, A. A.; Sadovski, O.; Woolley, G. A. J. Am. Chem. Soc. 2011, 133, 19684-19687. 41. Pang, Juan; Tian, Ziqi; Ma, Jing. Chemical Physics Letters. 2014, 613, 110-114. 42. Samanta, S.; Beharry, A. A.; Sadovski, O.; McCormick, T. M.; Babalhavaeji, A.; Tropepe V.; Woolley, G. A. J. Am. Chem. Soc. 2013, 135, 9777-9784. 43. Dong, M.; Babalhavaeji, A.; Collins, C. V.; Jarrah, K.; Sadovski, O.; Dai Qiuyun; Woolley, G. A. J. Am. Chem. Soc. 2017, 139, 13483-13486. 44. Liu, Danyang; Wang, Sijia; Xu, Shouhong; Liu, Honglai. Langmuir. 2017, 33, 1004–1012. 45. Montalbetti, C. A. G. N.; Falque, V. Tetrahedron. 2005, 61, 10827-10852.
摘要: In this thesis, we describe about drug delivery system and the uses of azobenzene amphiphilic moieties as a potential molecules toward liposome-based drug delivery. How to synthesize azobenzene amphiphilic structure is the point of this thesis and this article provides a reaction pathway to synthesize amphiphilic structure. In this article, we also test the photoswitch properties of the amphiphilic structure to determine the effectiveness of visible light radiation for azobenzene isomerization.
URI: http://hdl.handle.net/11455/97603
文章公開時間: 2018-08-31
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