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The effect of six weeks aerobic exercise training with different intensity on risk factors of cardiovascular disease in sedentary young adults
Aerobic Exercise Training
Risk Factors of Cardiovascular Disease
方法：本研究招募沒有抽菸習慣、每週運動小於一次無其他重大疾病的坐式生活型態健康年輕人，實驗期間被告知禁止飲酒，並維持生活型態。27人完成全部實驗流程，高強度組13人（年齡為22.7± 1.0歲，身高165.3± 8.5公分，體重57.1±9.9公斤）；低強度組14人（年齡為23.2± 1.6歲，身高166± 9.8公分。體重60.4±14.8公斤），所有受測者完成六週運動，每週三次、每次三十分鐘，高強度運動組以 85-95%HRmax進行訓練，低強度運動組以 65-75% HRmax訓練。訓練前後各測量血液樣本一次，分析心血管疾病風險因子指標包括：心跳血壓、血液生化、血液細胞激素。
結果：腰圍訓練後有顯著減少(p<0.001)，高強度組前後測與低強度前後測有顯著減少(p=0.013；p=0.003)。臀圍運動後有顯著減少(p=0.004)，高強度組前後測與低強度前後測皆有顯著減少(p=0.002；p=0.046)。體脂肪百分比訓練後有顯著減少(p<0.001) 高強度組前後測與低強度前後測皆顯著減少(p=0.00.3；p=0.035)。介白素-1β (IL-1β)訓練前後達顯著減少(p=0.003)，低強度組組內顯著減少(p=0.005)。介白素-10(IL-10)運動前後達顯著增加(p=0.031)，高強度組組內顯著增加(p=0.035)。
Introduction: Cardiovascular disease (CVD) is one of the leading cause of deaths worldwide. Sedentary lifestyle has been thought to be one of the major risk factors of CVD. Aerobic exercise is considered to be beneficial for improving cardio-respiratory fitness and reducing risks of CVD. This study was aimed to investigate 6 weeks aerobic exercise training with different intensities on CVD risk factors in young sedentary living style subjects. Methods: Twenty-eight healthy inactive subjects were recruited for the study. They were informed to avoid alcohol, smoking and were asked to maintain original life style during the experiment. Twenty-seven subjects completed experiment. Subjects were randomized to assign into high intensity exercise group (HE)(13 subjects, age:22.7± 1.0 years, Height 165.3± 8.5 cm, Weight :57.1±9.9 kg) and moderate intensity exercise group(ME)( 14 subject, age: 23.2± 1.6years, Height 166± 9.8cm, Weight : 60.4±14.8 kg). All of subjects were asked to complete 6 weeks exercise training (30 minutes per times, 3 times per week) at 85-95%HRmax in HE or at 65-75HRmax in ME. Anthropometric measurement and fasting blood samples were obtained before and after training. Plasma samples were analyzed for blood biochemistry and cytokines. Result : The results showed that there were significant changes in waist circumference after exercise training in both groups (HE: p=0.013 ; ME: p=0.003). In addition, hip circumference after exercise training in HE and ME group (p=0.002 ; p=0.046). Body fat percentage were found to reduce in both groups (HE: p=0.003: ME: p=0.035). Plasma IL-1β concentrations were significantly different after training in ME group (p=0.005). Plasma IL-10 concentrations were significantly different after training in HE group (p=0.035). Conclusion: Six weeks aerobic exercise training reduced CVD risk factors of body fat percentage, waist circumference, hip circumference in both groups. In the meantime, the anti-inflammatory cytokine IL-10 was increased in HE group and inflammatory cytokines IL-1β was decreased in ME group.
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