Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/98527
標題: 以舒泰化學保定鼬獾
Chemical Immobilization of the Formosan Ferret-badger (Melogale moschata subaurantiaca) with Tiletamine and Zolazepam
作者: 蕭舜庭
Shun-Ting Hsiao
關鍵字: 鼬獾
舒泰
化學保定
Formosan ferret-badger
Tiletamine-Zolazepam
Chemical immobilization
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摘要: 鼬獾(Melogale moschata subaurantiaca)是臺灣特有亞種,這種夜行性的食肉動物廣泛地分布於低中海拔地區。自從在2013年在鼬獾檢測出狂犬病後,相關研究便開始受到重視。為了有效率且安全地捕捉及保定鼬獾,此篇研究的目的為測試舒泰(tiletamine-zolazepam)應用於鼬獾的效果及安全性。舒泰被廣泛應用於保定野生動物,特別是食肉目動物。舒泰是由等重的tiletamine hydrochloride和zolazepam hydrochloride混合而成。這兩種藥物的結合提供了麻醉、輕度到中度的止痛,以及良好的肌肉鬆弛,但也需要較長的恢復時間。在我們的研究中,總共有十六隻(七公九母)誘捕自南投、花蓮和台東的鼬獾接受試驗。每一隻個體都接受六種舒泰劑量的肌肉注射(10.0 mg/kg, 12.5 mg/kg, 15.0 mg/kg, 17.5 mg/kg, 20.0 mg/kg, 22.5 mg/kg),並且同一隻於不同劑量的試驗至少間隔十四天。試驗中會記錄導入時間、開始恢復時間、翻正時間和完全恢復時間。麻醉保定期會每五分鐘記錄一次基礎生理值、反射和肌肉鬆弛程度。結果顯示15.0 mg/kg為最高失敗劑量。這十六隻鼬獾的最低麻醉劑量為17.5 mg/kg,此劑量的平均麻醉保定時間為21.5±9.0分鐘。麻醉的影響和恢復的時間與藥物劑量呈正相關。此篇研究的結論為以肌肉注射17.5 mg/kg至22.5 mg/kg的舒泰能有效保定鼬獾以進行測量及採樣,但其麻醉深度還不足以執行手術。
Formosan ferret-badger (Melogale moschata subaurantiaca) is an endemic subspecies to Taiwan, and this nocturnal carnivorous is wide distribution in low to middle altitude area. Since rabies had been detected in Formosan ferret-badger in 2013, related researches have been taken seriously. In order to capture and immobilize wild samples efficiently and safely, the aim of this study is to assess the effectiveness and safety of tiletamine-zolazepam (TZ) applied on Formosan ferret-badger. TZ has been used widely to restrain wildlife, especially carnivorous. It composes of equal parts by weights of tiletamine hydrochloride and zolazepam hydrochloride. The combination of the two drugs provides anesthesia, mild to moderate analgesia, and muscle relaxation, but also takes long recovery period. In our study, 16 adult wild Formosan ferret-badgers (7 males and 9 females) captured by clover traps from Nantou, Hualien, and Taitung were immobilized. Every individual accepted six dosages (10.0 mg/kg, 12.5 mg/kg, 15.0 mg/kg, 17.5 mg/kg, 20.0 mg/kg, 22.5 mg/kg) of TZ by intramuscular injection, and the trial interval between different dosages were at least fourteen days. In the trials, times of induction, initial recovery, righting, and full recovery were recorded. During the immobilization periods, vital signs, reflexes, and muscle tensions were measured every five minutes. The results were showed that the failure point was 15.0 mg/kg. The adequate anesthesia for 16 Formosan ferret-badgers was at least 17.5 mg/kg, and the average immobilization period of this dosage was 21.5±9.0 minutes. The anesthesia effects and recovery periods were positive correlations with the dosages. In conclusion, muscle injection of TZ between 17.5 mg/kg to 22.5 mg/kg provides effective immobilization in Formosan ferret-badger for measurements and sample collections, but the depth of anesthesia is not enough for surgery.
URI: http://hdl.handle.net/11455/98527
文章公開時間: 2018-08-27
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