Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/30729
標題: Regulation of yolk protein gene expression in the oriental fruit fly, Bactrocera dorsalis (Hendel), and establishment of its transgenic lines
東方果實蠅卵黃蛋白基因表現之調控與基因轉殖品系之建立
作者: Chen, Shiu-Ling
陳秀玲
關鍵字: http://etds.lib.nchu.edu.tw/etdservice/view_metadata?etdun=U0005-0402201017204500;東方果實蠅;卵黃蛋白;基因轉殖;r基因表現調控
出版社: 昆蟲學系所
引用: Abel, T., R. Bhatt and T. Maniatis. 1992. A Drosophila CREB/ATF transcriptional activator binds to both fat body- and liver-specific regulatory elements. Genes Dev. 6: 466-480. Abrahamsen, N., A, Martinez, T. Kjær, L. Søndergaard and M. Bownes. 1993. Cis-regulatory sequences leading to female-specific expression of yolk protein genes 1 and 2 in the fat body of Drosophila melanogaster. Mol. Gen. Genet. 237: 41-48. Adams, T. S., H. Hagedorn and G. D. Wheelock. 1985. Haemolymph ecdysteroid in the housefly, Musca domestica, during oogenesis and its relationship with vitellogeinin levels. J. Insect Physiol. 31: 91-97. Agui, N., T. Shimada, S. Izumi and S. Tomino. 1991. Hormonal control of vitellogenin mRNA levels in the male and female housefly, Musca domestica. J. Insect Physiol. 37: 383-390. Alphy, L. 2002. Re-engineering the sterile insect technique. Insect Biochem. Mol. Biol. 32: 1243-1247. Alphy, L., D. Nimmo, S. O'Connell and N. Alphey. 2008. Insect population suppression using engineered insects. Adv. Exp. Med. Biol. 627: 93-103. Amdam, G. V., Z. L. Simões, K. R. Guidugli, K. Norberg and S. W. Omholt. 2003. Disruption of vitellogenin gene function in adult honeybees by intra-abdominal injection of double-stranded RNA. BMC Biotechnol. 3: 1-8. An, W. and P. C. Wensink. 1995a. Integrating sex- and tissue-specific regulation within a single Drosophila enhancer. Genes Dev. 9: 256-266. An, W. and P. C. Wensink. 1995b. Three protein binding sites form an enhancer that regulates sex- and fat body-specific transcription of Drosophila yolk protein genes. EMBO J. 14: 1221-1230. Antoniewski, C., M. Laval, A. Dahan and J. A. Lepesant. 1994. The ecdysone response enhancer of the Fbp1 gene of Drosophila melanogaster is a direct target for the EcR/USP nuclear receptor. Mol. Cell. Biol. 14: 4465-4474. Antoniewski, C., B. Mugat, F. Delbac and J. A. Lepesant. 1996. Direct repeats bind the EcR/USP receptor and mediate ecdysteroid response in Drosophila melanogaster. Mol. Cell. Biol. 16: 2977-2986. Arnosti, D. N. 2002. Design and function of transcriptional switches in Drosophila. Insect Biochem. Mol. Biol. 32: 1257-1273. Arnosti, D. N. 2003. Analysis and function of transcriptional regulatory element: Insights from Drosophila. Annu. Rev. Entomol. 48: 579-602. Ashburner, M., C. Chihara, P. Meltzer and G. Richards. 1974. Temporal control of puffing activity in polytene chromosomes. Cold Spring Harb. Symp. Quant. Biol. 38: 655-662. Atkinson, P. W. 2002. Genetic engineering in insects of agricultural importance. Insect Biochem. Mol. Biol. 32: 1237-1242. Attardo, G. M., I. A. Hansen and A. S. Raikhel. 2005. Nutritional regulation of vitellogenesis in mosquitoes: Implications for anautogeny. Insect Biochem. Mol. Biol. 35: 661-675. Attardo, G. M., S. Higgs, K. A. Klingler, D. L. Vanlandingham and A. S. Raikhel. 2003. RNA interference-mediated knockdown of a GATA factor reveals a link to anautogeny in the mosquito Aedes aegypti. Proc. Natl. Acad. Sci. USA 100: 13374-13379. Baeuerle, P. A. and W. B. Huttner, 1985. Tyrosine sulfation of yolk proteins 1, 2, and 3 in Drosophila melanogaster. J. Biol. Chem. 260: 6434-6439. Baeuerle, P. A. and W. B. Huttner, 1987. Tyrosine sulfation is a trans-Golgi-specific protein modification. J. Biol. Chem. 105: 2655-2664. Barnett, T., C. Pachl, J. P. Gergen and P. C. Wensink. 1980. The isolation and characterization of Drosophila yolk protein genes. Cell 21: 729-738. Barr, P. J., O. B. Mason, K. E. Landsberg, P. A. Wong, M. C. Kiefer and A. J. Brake. 1991. cDNA and gene structure for a human subtilisin-like protease with cleavage specificity for paired basic amino acid residues. DNA Cell Biol. 19: 319-328. Bellés, X. 2005. Vitellogenesis directed by juvenile hormone. In: Raikhel, A. S. and T. W. Sappington (Eds.) Reproductive Biology of Invertebrates. Vol. XII Part B, Recent Progress in Vitellogenesis. Science Publisher, Inc., Enfiled (NH). pp. 158-197. Bernstein, E., A. A. Caudy, S. M. Hammond and G. J. Hannon. 2001. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409: 363-366. Bonizzoni, M., L. M. Gomulsi, A. R. Malacrida, P. Capy and G. Gasperi. 2007. Highly similar piggyBac transposase-like sequences from various Bactrocera (Diptera, Tephritidae) species. Insect Mol. Biol. 16: 645-650. Bownes, M. 1992. Why is there sequence similarity between insect yolk proteins and vertebrate lipases? J. Lipid Res. 33: 777-780. Bownes, M. 1994. The regulation of the yolk protein genes, a family of sex differentiation genes in Drosophila melanogaster. BioEssays 14: 745-752. Bownes, M. 2005. The regulation of yolk protein gene expression and vitellogenesis in higher Diptera. In: Raikhel, A. S. and T. W. Sappington (Eds.) Reproductive Biology of Invertebrates. Vol. XII Part B, Recent Progress in Vitellogenesis. Science Publisher, Inc., Enfiled (NH). pp. 95-128. Bownes, M. and M. Blair. 1986. The effects of a sugar diet and hormones on the expression of the Drosophila yolk protein genes. J. Insect Physiol. 32: 493-501. Bownes, M. and S. Pathirana. 2002. The yolk proteins of higher Diptera. In: Raikhel, A. S. and T. W. Sappington (Eds.) Reproductive Biology of Invertebrates. Vol. XII Part A, Recent Progress in Vitellogenesis. Science Publisher, Inc., Enfiled (NH). pp. 103-130. Bownes, M. and H. Rembold. 1987. The titre of juvenile hormone during the pupal and adult stages of the life cycle of Drosophila melanogaster. Eur. J. Biochem. 164: 709-712. Bownes, M., E. Ronaldson and D. Mauchline. 1996. 20-Hydroxyecdysone, but not juvenile hormone, regulation of yolk protein gene expression can be mapped to cis-acting DNA sequences. Dev. Biol. 173: 475-489. Bownes, M., S. Scott and M. Blair. 1987. The use of an inhibitor of protein synthesis to investigate the roles of ecdysteroids and sex-determination genes on the expression of the genes encoding the Drosophila yolk proteins. Development 101: 931-941. Bownes, M., E. Ronaldson, D. Mauchline and A. Martinez. 1993. Regulation of vitellogenesis in Drosophila. Int. J. Insect Morphol. Embryol. 22: 349-367. Bownes, M., A. Shirras, M. Blair, J. Collins and A. Coulson. 1988. Evidence that insect embryosgenesis is regulated by ecdysteroids released from yolk proteins. Proc. Natl. Acad. Sci. USA 85: 1554-1557. Bradley, J. T. and B. H. Estridge. 1997. Vitellogenin uptake and vitellin localization in insect follicles examined using monoclonal antibodies and confocal scanning microscopy. Invert Reprod. Dev. 32: 245-257. Brennan, M., A. Weiner, T. Goralski and A. Mahowald. 1982. The follicle cells are a major site of vitellogenin synthesis in Drosophila melanogaster. Dev. Biol. 89: 225-236. Brunak, S., J. Engelbrecht and S. Knudsen. 1991. Prediction of human mRNA donor and acceptor sites from the DNA sequence. J. Mol. Biol. 220: 49-65. Bulenda, D., A. Stecher, M. Freurek and K. H. Hoffman. 1986. Ecdysone metabolism in adult crickets. Insect Biochem. 16: 83-90. Burtis, K. C. and B. S. Baker. 1989. Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides. Cell 56: 997-1010. Burtis, K. C., K. T. Coschigano, B. S. Baker and P. C. Wensink. 1991. The Doublesex proteins of Drosophila melanogaster bind directly to a sex-specific yolk protein gene enhancer. EMBO J .10: 2577-2582. Butterworth, F. M., V. S. Burde, D. Mauchline and M. Bownes. 1999. A yolk protein mutant leads to defects in the secretion machinery of Drosophila melanogaster. Tissue Cell. 31: 212-222. Catteruccia, F., T. Nolan, T. G. Loukeris, C. Blass, C. Savakis, F. C. Kafatos and A. Crisanti. 2000. Stable germline transformation of the malaria mosquito Anopheles stephensi. Nature 405: 959-962. Chapman, R. F. 1998. Fat body. In: The Insects: Structure and Function, 4th edition. Cambridge University Press. pp.132-141. Chen, A. C., H. R. Kim, R. T. Mayer and J. O. Norman. 1987. Vitellogenesis in the stable fly, Stomoxys calcitrans. Comp. Biochem. Physiol. B 88: 897-903. Chen, J. H., P. C. Turner and H. H. Rees. 2002. Molecular cloning and induction of nuclear receptors from insect cell lines. Insect Biochem. Mol. Biol. 32: 657-667. Chen, L., J. Zhu and A. S. Raikhel. 2004. The early gene Broad is involved in the ecdysteroid hierarchchy governing vitellogenesis of the mosquito Aedes aegypti. J. Cell. Endocrinol. 33: 743-761. Chen, S. L. 2001. Cloning and structural analysis of vitellogenin genes of the oriental fruit fly, Bactrocera dorsalis (Hendel), Master's Thesis, Department of Entomology, National Chung Hsing University. 87pp. (in Chinese) Chiu, H. T. 1987. Studies on the improvement of mass rearing for oriental fruit flies. Plant Prot. Bull. 20: 87-92. (in Chinese) Christiansen, A. E., E. L. Keisman, S. M. Ahmad and B. S. Baker. 2002. Sex comes in from the cold: the integration of sex and pattern. Trends Genet. 18: 510-516. Christophides, G. K., L, Livadaras, C. Savakis and K. Komitopoulou. 2000. Two medfly promoters that have originated by recent gene duplication drive distinct sex, tissue and temporal expression patterns. Genetics 156: 173-182. Cho, W. L., M. Z. Kapitskaya and A. S. Raikhel. 1995. Mosquito ecdysteroid receptor- analysis of the cDNA and expression during vitellogenesis. Insect Biochem. Mol. Biol. 25: 19-27. Chung, Y. D., H. C. Kwon, K. W. Chung, S. J. Kim, K. Kim and C. C. Lee. 1996. Identification of ovarian enhancer-binding factors which bind to ovarian enhancer 1 of Drosophila genes Yp1 and Yp2. Mol. Gen. Genet. 251: 347-351. Comas, D., M. D. Piulachs and X. Bellés. 1999. Fast induction of vitellogenin gene expression by juvenile hormone III in the cockroach Blattella germanica (L.) (Dictyoptera, Blettellidae). Insect Biochem. Mol. Biol. 29: 821-827. Corona, M., R. A. Remolina, A. Moran-Lauter, K. A. Hughes and G. E. Robinson. 2007. Vitellogenin, juvenile hormone, insulin signaling, and queen honey bee longevity. Proc. Natl. Acad. Sci. USA 104: 7128-7133. Coschigano, K. T. and P. C. Wensink. 1993. Sex-specific transcriptional regulation by the male and female doublesex proteins of Drosophila. Genes Dev. 7: 42-54. Deitsch, K. W., N. Dittmer, M. Z. Kapitskaya, J. S. Chen, W. L. Cho and A. S. Raikhel. 1995. Regulation of gene expression by 20-hydroxyecdysone in the fat body of Aedes aegypti (Diptera: Culicidae). Eur. J. Entomol. 92: 237-244. DiMario, P. J. and A. P. Mahowald. 1987. Female sterile (1) yolkless: a recessive female sterile mutation in Drosophila melanogaster with depressed numbers of coated pits and coated vesicles within the developing oocytes. J. Cell Biol. 105: 199-206. Dhadialla, T. S. and A. S. Raikhel. 1990. Biosynthesis of mosquito vitellogenin. J. Biol. Chem. 265: 9924-9933. Fagotto, F. 1995. Regulation of yolk degradation, or how to make sleepy lysosomes. J. Cell Sci. 108: 3645-3647. Falb, D. and T. Maniatis. 1992a. A conserved regulatory unit implicated in the tissue-specific gene expression in Drosophila and man. Genes Dev. 6: 454-465. Falb, D. and T. Maniatis. 1992b. Drosophila transcriptional repressor protein that binds specifically to negative control elements in fat body enhancers. Mol. Cell. Biol. 12: 4093-4103. Falb, D., J. Fischer, T. Maniatis. 1992. Rearrangement of upstream regulatory elements leads to ectopic expression of the Drosopahila mulleri Adh-2 gene. Genetics 132: 1071-1079. Friederich, E., H. J. Fritz and W. B. Huttner. 1988. Inhibition of tyrosin sulfation in the trans-Golgi retards the transport of a constitutively secreted protein to the cell surface. J. Cell. Biol. 107: 1655- 1667. Garabedian, M. J., A. D. Shirras, M. Bownes and P. C. Wensink. 1987. The nucleotide sequence of the gene coding for Drosophila melanogaster yolk protein 3. Gene 55: 1-8. Garrett-Engele, C. M., M. L. Siegal, D. S. Manoli, B. C. Williams, H. Li and B. S. Baker. 2002. intersex, a gene required for female sexual development in Drosophila, is expressed in both sexes and functions together with doublesex to regulate terminal differentiation. Development 129: 4661-4675. Giorgi, F., J. T. Bradley and J. H. Nordin. 1999. Differential vitellin polypeptide processing in insect embryos. Micron 30: 579-596. Giorgi, F., A. Cecchettini, A. Falleni, M. Masetti and V. Gremigni. 1998. Vitellogenin is glycosylated in the fat body of the stick insect Carausius morosus and not further modified upon transfer to the ovarian follicle. Micron 29: 451-460. Gong, P., M. J. Epton and G. Fu. 2005. A dominant lethal genetic system for autocidal control of the Mediterranean fruitfly. Nat. Biotech. 23: 453-456. Gruntenki, N. E. and I. Y. Rauschenbach. 2008. Interplay of JH, 20E and biogenic amines under normal and stress conditions and its effect on reproduction. J. Insect Physiol. 54: 902-908. Guidugli, K. P., A. M. Nascimento, G. V. Amdam, A. R. Barchuk, S. Omholt, Z. L. P. Simoes and K. Hartfelder. 2005. Vitellogenin regulates hormonal dynamics in the worker caste of a eusocial insect. FEBS Lett. 579: 4961-4965. Hagedorn, H. H. 1985. The role of ecdysteroids in reproduction. In: Kerkut, G. A. and L. I. Gilbert (Eds.) Comprehensive Insect Physiology, Biochemistry and Pharmacology. Vol. 8. Pergamon. Oxford. pp. 205-261. Hagedorn, H. H. and A. M. Fallen. 1973. Ovarian control of vitellogenin synthesis by the fat body in Aedes aegypti. Nature 244: 103-105. Hagedorn, H. H., D. R. Maddison and Z. Tu. 1998. The evolution of vitellogenins, cyclorrhaphan yolk proteins and related molecules. Adv. Insect Physiol. 27: 335-384. Hames, B. D. and M. Bownes. 1978. Synthesis of yolk proteins in Drosophila melanogaster. Insect Biochem. 8: 319-328. Handler, A. M. 1997. Developmental regulation of yolk protein gene expression in Anastrepha suspensa. Arch. Insect Biochem. Physiol. 36: 25-35. Handler, A. M. 2000. An introduction to the history and methodology of insect gene transfer. In: Handler, A. M. and A. A. James (Eds.) Insect Transgenesis- Methods and Applications. CRC Press LLC. pp. 3-26. Handler, A. M. 2002a. Use of the piggyBac transposon for germline transformation of insects. Insect Biochem. Mol. Biol. 32: 1211-1220. Handler, A. M. 2002b. Prospects for using genetic transformation for improved SIT and new biocontrol methods. Genetica 116: 137-149. Handler, A. M. and R. A. Harrell. 1999. Germline transformation of Drosophila melanogaster with the piggyBac transposon vector. Insect Mol. Biol. 8: 449-457. Handler, A. M. and R. A. Harrell. 2001a. Polyubiquitin-regulated DsRed marker for transgenic insects. Biotechniques 31: 820-828. Handler, A. M. and R. A. Harrell. 2001b. Transformation of the Caribbean fruit fly with a piggyBac transposon vector marked with polyubiquitin-regulated GFP. Insect Biochem. Mol. Biol. 31: 199-205. Handler, A. M. and S. D. McCombs. 2000. The moth transposon, piggyBac, mediates germ-line transformation in the oriental fruit fly and exists in its genome. Insect Mol. Biol. 9: 605-612. Handler, A. M., S. D. McCombs, M. J. Fraser Jr. and S. H. Saul. 1998. The lepidopteran transposon vector piggyBac, mediates germline transformation in the Mediterranean fruit fly. Proc. Natl. Acad. Sci. USA 95: 7520-7525. He, M. and D. S. Haymer. 1994. The actin gene family in the oriental fruit fly Bactrocera dorsalis. Muscle specific actins. Insect Biochem. Mol. Biol. 24: 891-906. Hebsgaard, S. M., P. G. Korning, N. Tolstrup, J. Engelbrecht, P. Rouzé and S. Brunak. 1996. Splice site prediction in Arabidopsis thaliana pre-mRNA by combining local and global sequence information. Nucleic Acids Res. 24: 3439-3452. Hediger, M., G. Burghardt, C. Siegenthaler, N. Buser, D. Hilfiker-Kleiner, A. Dubendorfer and D. Bopp. 2004. Sex determination in Drosophila melanogaster and Musca domestica converges at the level of the terminal regulator doublesex. Dev. Genes. Evol. 214: 29-42. Heinrich, J. C. and M. J. Scott. 2000. A repressible female-specific lethal genetic system for making transgenic insect strains suitable for a sterile-release program. Proc. Natl. Acad. Sci. USA 97: 8229-8232. Heinrich, J. C., X. Li, R. A. Henry, N. Haack, L. Stringfellow, A. C. G. Heath and M. J. Scott. 2000. Germ-line transformation of the Australian sheep blowfly Lucilia cuprina. Insect Mol. Biol. 11: 1-10. Hens, K., P. Lemey, N. Macours, C. Francis and R. Huybrechts. 2004. Cyclorraphan yolk proteins and lepidopteran minor yolk proteins originate from two unrelated lipase families. Insect Mol Biol. 13: 615-623. Higgs, S. and D. Lewis. 2000. Green fluorescent protein (GFP) as a marker for transgenic insects. In: Handler, A. M. and A. A. James (Eds.) Insect Transgenesis: Methods and Application. CRC Press, Boca Raton. pp. 93-108. Hirai, M., D. Watanabe, A. Kiyota and Y. Chinzei. 1998. Nucleotide sequence of vitellogenin mRNA in the bean bug Riptortus clavatus: analysis of processing in the fat body and ovary. Insect Biochem. Mol. Biol. 28: 537-547. Hiremath, S. and K. Lehtoma. 1997. Structure of the gypsy moth vitellogenin gene. Arch. Insect Biochem. Physiol. 36: 151-164. Houseman, J. G. and P. E. Morrison. 1986. Absence of female-specific protein in the hemolymph of stable fly Stomoxys calcitrans (L.) (Diptera: Muscidae). Arch. Insect Biochem. Physiol. 3: 205-213. Hovemann, B., R. Galler, U. Walldorf, H. Küpper and E. K. F. Bautz. 1981. Vitellogenin in Drosophila melanogaster: sequence of the yolk protein I gene and its flanking regions. Nucleic Acids Res. 9: 4721-4734. Hung, M. C. and P. C. Wensink. 1983. Sequence and structure conservation in yolk proteins and their genes. J. Mol. Biol. 164: 481-492. Hutson, S. F. and M. Bownes. 2003. The regulation of yp3 expression in the Drosophila melanogaster fat body. Dev. Genes Evol. 213: 1-8. Huybrechts, R. and A. De Loof A. 1982. Similarities in vitellogenin and control of vitellogenin synthesis within the genera Sarcophaga, Calliphora, Phormia and Lucia (Diptera). Comp. Biochem. Physiol. 72B: 339-344. Isaac, P. G. and M. Bownes. 1982. Ovarian and fat-body vitellogenin synthesis in Drosophila melanogaster. Eur. J. Biochem. 123: 527-534. Kapetanaki, M. G., T. G. Loukeris, I. Livadaras and C. Savakis. 2002. High frequencies of Minos transposon mobilization are obtained in insects by using in vitro synthesized mRNA as a source of transposase. Nucleic Acids Res. 30: 3333-3340. Keisman, E. L., A. E. Christiansen and B. S. Baker. 2001. The sex determination gene doublesex regulates the A/P organizer to direct sex-specific patterns of growth in the Drosophila genital imaginal disc. Dev. Cell 11: 215-225. Kiehart, D. P., J. M. Crawford and R. A. Montague. 2000. Quantitative microinjection of Drosophila embryos. In: Sullivan, W., M. Ashburner and R. S. Hawley (Eds.) Drosophila Protocol. Cold Spring Harbor Laboratory Press, New York. pp. 345-359. Klowden, M. J. 1997. Endocrine aspects of mosquito reproduction. Arch. Insect Biochem. Physiol. 35: 491-512. Knudsen, S. 1999. Promoter 2.0: for the recognition of Pol III promoter sequences. Bioinformatics 15: 356-361. Kokoza, V. A., A. Ahmed, E. A. Wimmer and A. S. Raikhel. 2001a. Efficient transformation of the yellow fever mosquito Aedes aegypti using the piggyBac transposable element vector pBac[3xP3-EGFP afm]. Insect Biochem. Mol. Biol. 31: 1137-1143. Kokoza, V. A., A. Ahmed, W. L. Cho, N. Jasinskiene and A. A. James. 2000. Engineering blood meal-activated systemic immunity in the yellow fever mosquito, Aedes aegypti. Proc. Natl. Acad. Sci. USA 97: 9144-9149. Kokoza, V. A., D. Martin, M. J. Mienaltowski, A. Ahmed, C. M. Morton and A. S. Raikhel. 2001b. Transcriptional regulation of the mosquito vitellogenin via a blood meal-triggered cascade. Gene 274: 47-65. Lagueux, M., P. Harry and J. A. Hoffman. 1981. Ecdysteroids are bound to vitellin in newly laid eggs of Locusta. Mol. Cell. Endocrinol. 24: 325-338. Lan, O., K. Hiruma, X. Hu, M. Jindra and L. M. Riddiford. 1999. Activation of a delayed-early gene encoding MHR3 by the ecdysone receptor heterodimer EcR-B1-USP-1 but not by EcR-B1-USP-2. Mol. Cell. Biol. 19: 4897-4906. Lee, H. S., J. A. Simon and J. T. Lis. 1988. Structure and expression of ubiquitin genes of Drosophila melanogaster. Mol. Cell Biol. 8: 4727-4735. Lee, J. M., M. Hatakeyama and K. Oishi. 2000. A simple and rapid method for cloning insect vitellogenin cDNA. Insect Biochem. Mol. Biol. 30: 189-194. Levedakou, E. N. and C. E. Sekeris. 1987. Isolation and characterization of vitellin from the fruitfly, Dacus oleae. Arch. Insect Biochem. Physiol. 4: 297-311. Li, C. and B. S. Barker. 1998. Hemaphrodite and doublesex function both dependently and independently to control various aspects of sexual differentiation in Drosophila. Development 125: 2641-2651. Li, C., M. Z. Kapitskaya, J. Zhu, K. Miura, W. Segraves and A. S. Raikhel. 2000. Conserved molecular mechanism for stage specificity of the mosquito vitellogenic response to ecdysone. Dev. Biol. 224: 96-110. Li, X., J. C. Heinrich and M. J. Scott. 2001. piggyBac-mediated transposition in Drosophila melanogaster: an evaluation of the use of constitutive promoters to control transposase gene expression. Insect Mol. Biol. 10: 447-455. Lin, C. P. 1999. Isolation and identification of a yolk protein gene of the oriental fruit fly, Bactrocera dorsalis (Hendel), Master's Thesis, Department of Entomology, National Chung Hsing University. 68pp. (in Chinese) Liddell, S. and M. Bownes. 1991a. Characterization, molecular cloning and sequencing of YPsl, a fertile yolk protein 3 mutant in Drosophila. Mol. Gen. Genet. 228: 81-88. Liddell, S. and M. Bownes. 1991b. Investigation of cis-acting sequences regulating expression of the gene encoding yolk protein 3 in Drosophila melanogaster. Mol. Gen. Genet. 230: 219-224. Logan, S. K. and P. C. Wensink. 1990. Ovarian follicle cell enhancers from the Drosophila yolk protein genes: different segments of one enhancer have different cell-type specificities that interact to give normal expression. Genes Dev. 4: 613-623. Logan, S. K., M. J. Garabedian and P. C. Wensink. 1989. DNA regions that regulate the ovarian transcriptional specificity of Drosophila yolk protein genes. Genes Dev. 3: 1453-1461. Lombardo, F., M. D. Cristina, L. Spanos, C. Louis, M. Coluzzi and B. Arcà. 2000. Promoter sequences of the putative Anopheles gambiae apyrase confer salivary gland expression in Drosophila melanogaster. J. Biol. Chem. 275: 23861-23868. Lombardo, F., T. Nolan, G. Lycett, A. Lanfrancotti, N. Stich, F. Catteruccia, C. Louis, M. Coluzzi and B. Arcà. 2005. An Anopheles gambiae salivary gland promoter analysis in Drosophila melanogaster and Anopheles stephensi. Insect Mol. Biol. 14: 207-216. Lossky, M. and P. C. Wensink. 1995. Regulation of Drosophila yolk protein genes by an ovary-specific GATA factor. Mol. Cell. Biol. 15: 6943-6952. Lu, H. L. and K. H. Lu. 2003. Purification, characterization, and antibody preparation of vitellins of the oriental fruit fly, Bactrocera dorsalis (Diptera: Tephritidae). Formosan Entomol. 23: 87-99. (in Chinese) Martín, D., S. F. Wang and A. S. Raikhel. 2001 The vitellogenin gene of the mosquito Aedes aegypti is a direct target of ecdysteroid receptor. Mol. Cell. Endocrinol. 173: 75-86. Martín, D., M. Geoffery, M. Attardo and I. A. Hansen. 2005. Molecular mechanisms of tissue-specific gene expression in insects. In: Raikhel, A. S. and T. W. Sappington (Eds.) Reproductive Biology of Invertebrates. Vol. XII Part B, Recent Progress in Vitellogenesis. Science Publisher, Inc., Enfiled (NH). pp. 130-156. Martinez, A. and M. Bownes. 1994. The sequence and expression pattern of the Calliphora erythrocephala yolk protein A and B genes. J. Mol. Evol. 38: 336-351. McInnis, D. O., T. E. Shelly and J. Komatsu. 2002. Improving male competitiveness and survival in the field for Medfly, Ceratitis capitata (Diptera: Tephritidae) SIT programs. Genetica 116: 117-124. Miura, K., S. F. Wang and A. S. Raikhel. 1999. Two distinct subpopulations of ecdysone receptor complex in the female mosquito during vitellogenesis. Mol. Cell. Endocrinol. 156: 111-120. Miura, K., J. Zhu. N. T. Dittmer, L. Chen and A. S. Raikhel. 2002. A COUP-TF/Svp homolog is highly expressed during vitellogenesis in the mosquito Aedes aegypti. J. Mol. Endocrinol. 29: 223-238. Moto, K., S. E. Salam, S. Sakurai and M. Iwami. 1999. Gene transfer into insect brain and cell-specific expression of bombyxin gene. Dev. Genes. Evol. 209: 447-450. Myers, J. W., J. T. Jones, T. Meyer and J. E. Ferrell Jr. 2003. Recombinant Dicer efficiently converts large dsRNAs into siRNAs suitable for gene silencing. Nat. Biotechnol. 21: 324-328. Nelson, C. M., K. E. Ihle, M. K. Fondrk, R. E. Page and G. V. Amdam. 2007. The vitellogenin gene has multiple coordinating effects on social organization. PLoS Biol. 5, e62. O'Brochta, D. A., P. W. Atkinson and M. L. Lehane. 2000. Transformation of Stomoxys calcitrans with a Hermes gene vector. Insect Mol. Biol. 9: 531-538. Pan, M. L., W. J. Bell and W. H. Tefler. 1969. Vitellogenic blood protein synthesis by insect fat body. Science 165: 393-394. Park, J. H., G. M. Attardo, I. A. Hansen and A. S. Raikhel. 2006. GATA factor translation is the final downstream step in the amino acid/target-of- rapamycin-mediated vitellogenin gene expression in the anautogenous mosquito Aedes aegypti. J. Biol. Chem. 281: 11167-11176. Peloquin, J. J., S. T. Thibault, R. Staten and T. A. Miller. 2000. Germ-line transformation of pink bollworm (Lepidoptera: Gelechiidae) mediated by the piggyBac transposable element. Insect Mol. Biol. 9: 323-333. Pierceall, W. E., C. Li, A. Biran, K. Miura and A. S. Raikhel. 1999. E75 expression in mosquito ovary and fat body suggests reiterative use of ecdysone-regulated hierarchies in development and reproduction. Mol. Cell. Endocrinol. 150: 73-89. Pinkerton, A. C., K. Michel, D. A. O'Brochta and P. W. Atkinson. 2000. Green fluorescent protein as a genetic marker in transgenic Aedes aegypti. Insect Mol. Biol. 9: 1-10. Raikhel, A. S. and T. S. Dhadialla. 1992. Accumulation of yolk proteins in insect oocytes. Annu. Rev. Entomol. 37: 217-251. Raikhel, A. S. and A. O. Lea. 1990. Juvenile hormone controls previtellogenic proliferation of ribosomal RNA in the mosquito fat body. Gen. Comp. Endocrinol. 77: 423-434. Raikhel, A. S., M. Bownes and X. Belles. 2005. Hormonal control of reproductive processes. In: Gilbert, L., S. Gill and K. Iatrou (Eds.) Comprehensive Insect Physiology, Biochemistry, Pharmacology and Molecular Biology, Vol. 3. Elsevier Press, London, United Kingdom. pp. 433-491. Raikhel, A. S., V. A. Kokoza, J. Zhu, D. Martin, S. F. Wang, C. Li, G. Sun, A. Ahmed, N. Dittmer and G. Attardo. 2002. Molecular biology of mosquito vitellogenesis: from basic studies to genetic engineering of antipathogen immunity. Insect Biochem. Mol. Biol. 32: 1275-1286. Raphael, K. A., S. Whyard, D. Shearman, X. An and M. Frommer. 2004. Bactrocera tryoni and closely related pest tephritids- molecular analysis and prospects for transgenic control strategies. Insect Biochem. Mol. Biol. 34: 167-176. Riehle, M. A., P. Srinivasan, C. K. Moreira and M. Jacobs-Lorena. 2003. Towards genetic manipulation of wild mosquito populations to combat malaria: advances and challenges. J. Exp. Biol. 206: 3809-3816. Richard, D. S., N. L. Watkins, R. B. Serafin and L. I. Gilbert. 1998. Ecdysteroids regulate yolk protein uptake by Drosophila melanogaster oocytes. J. Insect Physiol. 44: 637-644. Richard, D. S., J. M. Jones, M. R. Barbarito, S. Cerula, J. P. Detweiler, S. J. Fisher, D. M. Brannigan and D. M. Scheswohl. 2001. Vitellogenesis in diapausing and mutant Drosophila melanogaster: further evidence for the relative roles of ecdysteroids and juvenile hormones. J. Insect Physiol. 47: 905-913. Riddihough, G. and H. R. B. Pelham. 1987. An ecdysone response element in the Drosophila hsp27 promoter. EMBO J. 6: 3729-3734. Rina, M. D. and A. C. Mintzas. 1988. Biosynthesis and regulation of two vitellogenins in the fat body and ovaries of Ceratitis capitata (Diptera). Roux''s Arch. Dev. Biol. 197: 167-174. Rina, M. D. and C. Savakis. 1991. A cluster of vitellogenin genes in the Mediterranean fruit fly Ceratitis capitata: sequence and structural conservation in dipteran yolk proteins and their genes. Genetics 127: 769-780. Robinson, A. S. 2002. Genetic sexing strains in medfly, Ceratitis capitata, sterile insect technique programmes. Genetica 116: 5-13. Robinson, A. S. and G. Franz. 2000. The application of transgenic insect technology in sterile insect technique. In: Handler, A. M and A. A. James (Eds.) Insect Transgenesis- Methods and Application. CRC Press, Boca Raton. pp. 307-318. Ronaldson, E. and M. Bownes. 1995. Two independent cis-acting elements regulate the sex- and tissue-specific expression of yp3 in Drosophila melanogaster. Gen. Res. 66: 9-17. Romans, P., Z. Tu, Z. Ke and H. Hagedorn. 1995. Analysis of a vitellogenin gene of the mosquito Aedes aegypti and comparisons to vitellogenins from organisms. Insect Biochem. Mol. Biol. 25: 939-958. Rubin, G. M. and A. C. Spradling. 1982. Genetic transformation of Drosophila with transposable element vectors. Science 218: 348-353. Rubacha, A., M. Tucker, T. de Valoir, E. Berlikoff and K. Beckingham. 1988. Genes with specific functions in ovarian follicles of Calliphora erythrocephala. Dev. Biol. 129:449-463. Sambrook, J. and D. W. Russell. 2001. In vitro amplification of DNA by the polymerase chain reaction. In: J. Sambrook and D. W. Russell, (Eds.) Molecular Cloning, A Laboratory Manual, Cold Spring Harbor Laboratory. Cold Spring Harbor Laboratory Press, New York. pp. 8.1-8.113. Sappington, T. W. 2002. The major yolk proteins of higher Diptera are homologs of a class of minor yolk proteins in Lepidoptera. J. Mol. Evol. 55: 470-475. Sappington, T. W. and A. S. Raikhel. 1998. Molecular characteristics of insect vitellogenins and vitellogenin receptor. Insect Biochem. Mol. Biol. 28: 277-300. Sappington, T. W., A. R. Hays and A. S. Raikhel. 1995. Mosquito vitellogenin receptor: purification, developmental and biochemical characterization. Insect Biochem. Mol. Biol. 25: 807-817. Sarkar, A., C. J. Coates, S. Whyard, U. Willhoeft, P. W. Atkinson and D. A. O'Brochta. 1997. The Hermes element from Musca domestica can transpose in four families of cyclorrhaphan flies. Genetica 99: 15-29. Sarkar, A., C. Sim, Y. S. Hong, J. R. Hogan, M. J. Fraser, H. M. Robertson and F. H. Collins. 2003. Molecular evolutionary analysis of the widespread piggyBac transposon family and related "domesticated" sequences. Mol. Genet. Genomics 270: 173-180. Schonbaum, C. P., S. Lee and A. P. Mahowald. 1995. The Drosophila yolkless gene encodes a vitellogenin receptor belonging to the low-density lipoprotein receptor superfamily. Proc. Natl. Acad. Sci. USA 92: 1485-1489. Schonbaum, C. P., J. J. Perrino and A. P. Mahowald. 2000. Regulation of vitellogenin receptor during Drosophila melanogaster oogenesis. Mol. Biol. Cell 11: 511-521. Shin, S. W., V. Kokoza and A. S. Raikhel. 2003a. Transgenesis and reverse genetics of mosquito innate immunity. J. Exp. Biol. 206: 3835-3843. Shin, S. W., V. Kokoza, I. Lobkov and A. S. Raikhel. 2003b. Relish-mediated immune deficiency in the transgenic mosquito Aedes aegypti. Proc. Natl. Acad. Sci. USA 100: 2616-2621. Snigirevskaya, E. S. and A. S. Raikhel. 2005. Receptor-mediated endosytosis in insect oocytes. In: A. S. Raikhel and T. W. Sappington (Eds.) Reproductive Biology of Invertebrates. Vol. XII Part B, Recent Progress in Vitellogenesis. Science Publisher, Inc., Enfiled (NH). pp. 199-228. Soller, M., M. Bownes and E. Kubli. 1997. Mating and sex peptide stimulate the accumulation of yolk in oocytes of Drosophila melanogaster. Eur. J. Biochem. 243: 732-738. Soller, M., M. Bownes and E. Kubli. 1999. Control of oocyte maturation in sexually mature Drosophila females. Dev. Biol. 208: 337-351. Stoffolano, J. G., M. F. Li, B. X. Zoe and C. M. Yin. 1992. Vitellogenin uptake, not synthesis, is dependent on juvenile-hormone in adults of Phormia regina (Mrigen). J. Insect Physiol. 38: 839-845. Sun, G. Q., J. S. Zhu and A. S. Raikhel. 2004. The early E74B isoform is a transcriptional activator of the ecdysteroid regulatory hierarchy in mosquito vitellogenesis. Mol. Cell. Endocrinol. 218: 95-105. Sun, G. Q., J. Zhu, L. Chen and A. S. Raikhel. 2005. Synergistic action of E74B and ecdysteroid receptor in activating a 20-hydroxyecdysone effector gene. Proc. Natl. Acad. Sci. USA 102: 15506-15511. Sun, G. Q., J. S. Zhu, C. Li, Z. J. Tu and A. S. Raikhel. 2002. Two isoforms of the early E74 gene, an Est transcription factor homologue, are implicated in the ecdysteroid hierarchy governing vitellogenesis of mosquito, Aedes aegypti. Mol. Cell Endocrinol. 190: 147-157. Sun, J., T. Hirraoka, N. T. Dittmer, K. H. Cho and A. S. Raikhel. 2000. Lipoph
摘要: 
In current studies, a 2.7-kb upstream fragment of the putative promoter region of the oriental fruit fly, Bactrocera dorsalis yolk protein gene 1 (Bdyp1) was cloned, and the sequence comprises a series of potential regulatory elements responsible for the regulation of the gene expression, including six potential ecdysone response elements (EcREs), and numerous binding sites for various transcriptional factors, such as GATA, Doublesex, MAB-3, AEF-1, BBF-2, and others. Transient transfection analysis in Sf21 cells showed that the 2.4-kb frame of 5'-flanking region of Bdyp1 exhibits the greatest activity in response to the treatment with 10-2 nM of 20-hydroxyecdysone (20E). Moreover, promoter deletion and gel shift analysis further revealed that 20E is most likely interacting with the first two EcREs only. To address how transfactors regulate the Bdyp1 expression, RNA interference (RNAi) assays were used to demonstrate that female-specific Bddsx dsRNA not only specifically reduces its own transcript but also selectively inhibits the expression of Bdyp1 gene and delays the ovarian development. In addition, the properties of the Bdyp1 promoter were analyzed in vivo using germline transformation. The reporter gene, egfp, controlled by 2.4 and 0.4-kb of 5'-flank region of Bdyp1; and both exogenous genes were specifically expressed in fat body, indicating its tissue-specific expression of the yp1 promoter. However, the EGFP expression appears both in males and females, indicating loss of its sex-specific expression. It is thus speculated that loss of the sex-specificity in both transgenic lines may be caused by the position effect of transgenesis.

本研究選殖東方果實蠅(Bactrocera dorsalis (Hendel))(Tephritidae: Diptera)卵黃蛋白基因1(yolk protein gene 1, Bdyp1)之5’端調控、啟動子與基因本體部份核酸序列,經比對分析後得知調控區域具有蛻皮激素受器(ecdysone receptor, EcR)、雌性雙性基因(female specific doublesex, dsxF)、GATA factor、E75、adult expression factor (AEF)等激素、組織或性別表現專一性之轉錄因子(transcription factor)結合之反應位。於昆蟲細胞轉染(transfection)試驗中證實,卵黃蛋白基因啟動子會受激素誘發而活化,其中又以蛻皮激素(ecdysteroids)為主要調控激素,青春激素(juvenile hormone)僅具些微活化啟動子之效能,且蛻皮激素受器反應位(ecdysone response element, EcRE)之序列能與受蛻皮激素刺激之核蛋白結合,配合啟動子截切活性分析(promoter deletion assay)結果,顯示靠近轉錄起始位(transcription start code)之兩蛻皮激素受器反應位能受蛻皮激素刺激進而誘發卵黃蛋白基因表現,此部份結果與高等雙翅目昆蟲卵黃蛋白調控機制中所提之論點相符;再者,利用轉錄因子dsxf啟動RNA默化(RNA interference, RNAi)機制時,Bdyp1於基因及蛋白表現層次皆受到影響而有遲延表現之趨勢,卵巢發育亦明顯較注射雙股egfp之對照組緩慢。最後,藉由生殖細胞系的轉型作用(germline transformation)探討Bdyp1性別和組織表現之專一性,兩基因轉殖品系,pyp2.4與pyp0.4,之報導基因(綠色螢光蛋白)皆僅表現於脂肪體細胞而保留其組織專一性,但無法呈現預期之性別專一性,推測此現象乃由於基因轉殖外來片段時鑲嵌於染色體上位置效應(position effect)所導致。
URI: http://hdl.handle.net/11455/30729
其他識別: U0005-0402201017204500
Appears in Collections:昆蟲學系

Show full item record
 

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.