Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/32859
DC FieldValueLanguage
dc.contributor.authorLiu, J.J.en_US
dc.contributor.author張天傑zh_TW
dc.contributor.authorWong, M.L.en_US
dc.contributor.authorChang, T.J.en_US
dc.date1998zh_TW
dc.date.accessioned2014-06-06T07:44:18Z-
dc.date.available2014-06-06T07:44:18Z-
dc.identifier.issn0168-1702zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/32859-
dc.description.abstractThe cDNA of the nucleocapsid (core) protein of classical swine fever virus (CSFV) was generated by reverse transcription-polymerase chain reaction (RT-PCR) and cloned into a eukaryotic expression vector. The effect of the recombinant core protein on the transcriptional regulation of cellular as well as viral promoters was studied. Using transient transfection assay, our results demonstrated that the core protein can activate the promoter of human heat shock protein 70 gene, and suppressed the SV40 early promoter. These findings indicate that the core protein appears to function not only as a viral structural protein but also as a regulator of gene expression. The implications of core proteins on the viral maturation are discussed. (C) 1998 Elsevier Science B.V. All rights reserved.en_US
dc.language.isoen_USzh_TW
dc.relationVirus Researchen_US
dc.relation.ispartofseriesVirus Research, Volume 53, Issue 1, Page(s) 75-80.en_US
dc.relation.urihttp://dx.doi.org/10.1016/s0168-1702(97)00132-9en_US
dc.subjectclassical swine fever virusen_US
dc.subjectnucleocapsid proteinen_US
dc.subjecthog-cholera virusen_US
dc.subjectfull-length cdnaen_US
dc.subjectnucleotide-sequenceen_US
dc.subjectinfectiousen_US
dc.subjectrnaen_US
dc.subjectassociationen_US
dc.subjectpestivirusen_US
dc.subjectgenomeen_US
dc.titleThe recombinant nucleocapsid protein of classical swine fever virus can act as a transcriptional regulatoren_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1016/s0168-1702(97)00132-9zh_TW
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeJournal Article-
item.cerifentitytypePublications-
item.fulltextno fulltext-
item.languageiso639-1en_US-
item.grantfulltextnone-
Appears in Collections:獸醫學系所
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