Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/32981
DC FieldValueLanguage
dc.contributor.authorLiu, S.A.en_US
dc.contributor.author董光中zh_TW
dc.contributor.authorTung, K.C.en_US
dc.contributor.authorCheng, C.C.en_US
dc.contributor.authorChiu, Y.T.en_US
dc.date2008zh_TW
dc.date.accessioned2014-06-06T07:44:34Z-
dc.date.available2014-06-06T07:44:34Z-
dc.identifier.issn0937-4477zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/32981-
dc.description.abstractThe formation of pharyngo-cutaneous fistula (PCF) is controversial and various predisposing factors have been proposed. This study aimed to compare different suture materials in the closure of pharyngeal wounds in experimental animals. Fifty-two Sprague-Dawley rats were divided into three groups. Artificial pharyngotomy was performed and was then repaired with Vicryl, polypropylene, and Vicryl plus fibrin glue, respectively. Outcome measurements included gross wound inspection and histological examination. There was a significant difference in the rates of PCF formation between group I and group II (Fisher's exact test, p = 0.046). In addition, minimal inflammatory response was found in the polypropylene group when compared to the other groups. The fibrin glue-treated group had the highest fibroblast activity and collagen deposition. Polypropylene produced minimal tissue reaction, which facilitated the healing process. Therefore, proper selection of suture material can probably reduce the rate of PCF but should not be substituted for proper aseptic and meticulous surgical techniques.en_US
dc.language.isoen_USzh_TW
dc.relationEuropean Archives of Oto-Rhino-Laryngologyen_US
dc.relation.ispartofseriesEuropean Archives of Oto-Rhino-Laryngology, Volume 265, Issue 2, Page(s) 227-231.en_US
dc.relation.urihttp://dx.doi.org/10.1007/s00405-007-0431-9en_US
dc.subjectpharyngo-cutaneous fistulaen_US
dc.subjectsutureen_US
dc.subjectanimal modelen_US
dc.subjectpolypropyleneen_US
dc.subjectfibrinen_US
dc.subjectglueen_US
dc.subjectpharyngocutaneous fistulaen_US
dc.subjectsurgeryen_US
dc.subjectcanceren_US
dc.subject5-fluorouracilen_US
dc.subjectcomplicationsen_US
dc.subjectanastomosesen_US
dc.subjectimmediateen_US
dc.subjectlarynxen_US
dc.subjectheaden_US
dc.subjectglueen_US
dc.titleThe impact of different closure materials on pharyngeal wound healing: an experimental animal studyen_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1007/s00405-007-0431-9zh_TW
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.languageiso639-1en_US-
item.fulltextno fulltext-
item.grantfulltextnone-
item.openairetypeJournal Article-
Appears in Collections:獸醫學系所
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