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標題: Complete sequence of a subgroup 3.4 strain of classical swine fever virus from Taiwan
作者: Lin, Y.J.
Chien, M.S.
Deng, M.C.
Huang, C.C.
關鍵字: classical swine fever virus;historical strain;rapid amplification of;cDNA end (RACE);untranslated region (UTR);hepatitis-c virus;hog-cholera virus;5' nontranslated regions;viral;diarrhea virus;secondary structure;noncoding region;untranslated;region;european-union;entry site;pestivirus
Project: Virus Genes
期刊/報告no:: Virus Genes, Volume 35, Issue 3, Page(s) 737-744.
Classical swine fever viruses from Taiwan have been classified into two subgroups (3.4 and 2.1). Outbreaks caused by 3.4 viruses were reported in Taiwan prior to 1996 and which mainly distributed in the geographic range from southern Japan to Taiwan. We have determined the complete sequence of a reference strain, 94.4/IL/94/TWN. The genome contains 12,296 nucleotides, encoding 3,898 amino acids flanked by a 372-nt region at the 5' untranslated region (UTR) and a 227-nt region at the 3'-UTR. Similarities of nucleotides among 3.4 viruses isolated from Taiwan and Japan (Kanagawa/74; Okinawa/86) maintained in 94.2-97.5%; however, comparing to subgroup 1.1 (ALD/64/Jap) and 2.1 (TD/96/TWN) only showed about 72.5-80.8%, respectively. Phylogenetic analysis based on positioning from 11,157 to 11,565 nt (NS5B region) revealed that CSFVs were divided into three major lineages and their sublineages. Strain 94.4/IL/94/TWN is the first completely genomic sequence of subgroup 3.4 viruses.
ISSN: 0920-8569
DOI: 10.1007/s11262-007-0154-4
Appears in Collections:獸醫病理生物學所

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