Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/34198
標題: Using LC/MS/MS to determine matrine, oxymatrine, ferulic acid, mangiferin, and glycyrrhizin in the Chinese medicinal preparations Shiau-feng-saan and Dang-guei-nian-tong-tang
作者: Jong, T.T.
李茂榮
Lee, M.R.
Chiang, Y.C.
Chiang, S.T.
鍾婷婷
關鍵字: matrine;oxymatrine;ferulic acid;mangiferin;glycyrrhizin;Shiau-feng-saan;Dang-guei-nian-tong-tang;Sophorae Radix;Angelicae;sinensis Radix;Anemarrhena Rhizoma;Glycyrrhizae Radix;performance liquid-chromatography;mass-spectrometry;cinnamic acid;cinnamaldehyde
Project: Journal of Pharmaceutical and Biomedical Analysis
期刊/報告no:: Journal of Pharmaceutical and Biomedical Analysis, Volume 40, Issue 2, Page(s) 472-477.
摘要: 
We have developed a simple, rapid, selective, and reproducible method for the quality control of traditional Chinese medicinal preparations. In this study, we used LC/MS/MS to simultaneously identify and quantify five marker compounds - matrine, oxymatrine, ferulic acid, mangiferin, and glycyrrhizin - in preparations of Shiau-feng-saan and Dang-guei-nian-tong-tang. The calibration curves for the five marker compounds were linear over the concentration range 50-2500 ng/mL (R-2 > 0.9971). The matrix effect was minimized and the recoveries of the five marker compounds were > 90% at a concentration of 1 mu g/mL. Our experimental data reveal that significant differences exist between samples obtained from different sources. (c) 2005 Elsevier B.V. All rights reserved.
URI: http://hdl.handle.net/11455/34198
ISSN: 0731-7085
DOI: 10.1016/j.jpba.2005.07.036
Appears in Collections:化學系所

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