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標題: Voltammetric determination of serotonin in human blood using a chemically modified electrode
作者: Zen, J.M.
Chen, I.L.
Shih, Y.
關鍵字: serotonin;chemically modified electrode;human blood;platelets;oxidation
Project: Analytica Chimica Acta
期刊/報告no:: Analytica Chimica Acta, Volume 369, Issue 1-2, Page(s) 103-108.
A Nafion(R)/ruthenium-oxide pyrochlore chemically modified electrode (CME) was used for the determination of serotonin in human blood by square-wave voltammetry. Compared to a bare glassy carbon electrode, the chemically modified electrode exhibits a marked enhancement of the current response. With 45 s preconcentration time at a potential of -0.3 V vs. Ag/AgCl, linear calibration curves are obtained in pH 9 ammonia buffer over 0.01-0.5 mu M and 2-20 mu M with a detection limit (3 sigma) of 2 nm. The chemically modified electrode was applied for the measurement of serotonin in human blood. (C) 1998 Elsevier Science B.V. All rights reserved.
ISSN: 0003-2670
DOI: 10.1016/s0003-2670(98)00232-3
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