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|標題:||Voltammetric determination of serotonin in human blood using a chemically modified electrode||作者:||Zen, J.M.
|關鍵字:||serotonin;chemically modified electrode;human blood;platelets;oxidation||Project:||Analytica Chimica Acta||期刊/報告no：:||Analytica Chimica Acta, Volume 369, Issue 1-2, Page(s) 103-108.||摘要:||
A Nafion(R)/ruthenium-oxide pyrochlore chemically modified electrode (CME) was used for the determination of serotonin in human blood by square-wave voltammetry. Compared to a bare glassy carbon electrode, the chemically modified electrode exhibits a marked enhancement of the current response. With 45 s preconcentration time at a potential of -0.3 V vs. Ag/AgCl, linear calibration curves are obtained in pH 9 ammonia buffer over 0.01-0.5 mu M and 2-20 mu M with a detection limit (3 sigma) of 2 nm. The chemically modified electrode was applied for the measurement of serotonin in human blood. (C) 1998 Elsevier Science B.V. All rights reserved.
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