Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/34862
DC FieldValueLanguage
dc.contributor.authorShih, Y.en_US
dc.contributor.author曾志明zh_TW
dc.contributor.authorZen, J.M.en_US
dc.contributor.authorYang, H.H.en_US
dc.date2002zh_TW
dc.date.accessioned2014-06-06T07:48:27Z-
dc.date.available2014-06-06T07:48:27Z-
dc.identifier.issn0731-7085zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/34862-
dc.description.abstractBoth flow-injection analysis and square-wave stripping voltammetry were evaluated for the determination of codeine in pharmaceutical formulations using a nontronite clay-modified screen-printed carbon electrode. Compared with a bare screen-printed carbon electrode, the nontronite clay-modified screen-printed carbon electrode exhibited a marked enhancement of the current response of codeine. A linear calibration plot was obtained over the 2.5-45 muM range (correlation coefficient = 0.999) in pH 6.0 phosphate buffer solution with a detection limit of 20 nM (S/N= 3) by square-wave voltammetry (SWV). While, in flow-injection analysis, the linearity was over 5-120 ng range with a detection limit of 1 ng in 20 mul loop. The nontronite clay-modified screen-printed carbon electrode can be either disposable or reused since the renewal gave a good reproducible surface. Quantitative analysis was performed by the standard addition method for codeine content in both urine and commercially available drugs. (C) 2002 Elsevier Science B.V. All rights reserved.en_US
dc.language.isoen_USzh_TW
dc.relationJournal of Pharmaceutical and Biomedical Analysisen_US
dc.relation.ispartofseriesJournal of Pharmaceutical and Biomedical Analysis, Volume 29, Issue 5, Page(s) 827-833.en_US
dc.relation.urihttp://dx.doi.org/10.1016/s0731-7085(02)00179-6en_US
dc.subjectcodeineen_US
dc.subjectclayen_US
dc.subjectscreen-printed carbon electrodeen_US
dc.subjectdrugen_US
dc.subjecturineen_US
dc.subjectperformance liquid-chromatographyen_US
dc.subjectgas-chromatographyen_US
dc.subjectpaste electrodesen_US
dc.subjectmorphineen_US
dc.subjectplasmaen_US
dc.subjectchemiluminescenceen_US
dc.subjectblooden_US
dc.titleDetermination of codeine in urine and drug formulations using a clay-modified screen-printed carbon electrodeen_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1016/s0731-7085(02)00179-6zh_TW
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.languageiso639-1en_US-
item.grantfulltextnone-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
item.fulltextno fulltext-
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