Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/3588
標題: 薑黃酮類與二氧化碳之高壓汽液相平衡與擬合計算
Vapor-Liquid Equilibria and correlation of Carbon Dioxide and Turmerones at Elevated Pressure
作者: 高龍吉
Kao, Lung-Chi
關鍵字: high-pressure vapor liquid equilibria;高壓汽液相平衡;turmerone;carbon dioxide;equation of state;correlation;薑黃酮;二氧化碳;狀態方程式模擬
出版社: 化學工程學系所
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摘要: 
中文摘要
本研究以超臨界二氧化碳,萃取中草藥原料薑黃的薑黃酮油。在313.15 K和260 bar的超臨界態下,經2.5小時萃取,可得到產率4.68 wt%至6.14 wt%的薑黃精油。接著以正相樹脂silica gel-60的管柱純化程序。使用正己烷和乙酸乙酯或丙酮的混合液,配成五種不同比例(體積比)的沖提液來進行沖提,提高薑黃精油中三種薑黃酮(ar-turmerone、α-turmerone和β-turmerone)的純度。實驗結果顯示,經50~60公分正相樹脂silica gel-60管柱純化分離後,薑黃酮純度可由67.6 wt%提昇至80.0 wt%以上。重複再經正相樹脂silica gel-60管柱純化分離後,最後可得薑黃酮純度91.8 wt%的薑黃精油。高壓汽液相平衡方面,以定體積靜態式裝置,搭配汽液相循環系統,並聯兩個震盪管密度儀,量測二氧化碳與薑黃酮之汽液相密度,相組成,及平衡常數。兩個研究溫度為313.15 K與333.15 K。壓力範圍由2.82至20.80 MPa。最後,薑黃酮汽液相平衡數據,代入PE模擬軟體中,分別以三種狀態方程式(PR-EOS、SRK-EOS、PT-EOS),搭配三種混合律(MR-Q、MR-AS、MR-PR)及兩種目標函數,來擬合得到液相組成及汽相組成的計算值。數據顯示平均相對偏差目標函數,較適合二氧化碳與薑黃酮油的汽相組成的擬合計算。

SUMMARY
This study mainly investigates high-pressure phase equilibria of turmerones and carbon dioxide. Supercritical carbon dioxide extraction at 313.15 K and 260 bar, produces 4.68% to 6.14% turmeric oil containing 67.7% purity of turmerones. A normal phase silica gel 60 column was then employed to purify three turmerones( ar-turmerone, α-turmerone and β-turmerone) from this turmerone-rich oil, and the oil containing 91.8% purity of turmerones was obtained. A static phase equilibrium apparatus with two magnetic circulation pumps was capable of providing vapor and liquid composition data for a binary mixture of turmerone and CO2 at 313.15 and 333.15 K, pressures ranged from 2.82 MPa to 20.80 MPa. Liquid and vapor densities for this high-pressure carbon dioxide + turmerone solution were also obtained. The vapor-liquid equilibrium data were finally correlated using three equations of state(PR-EOS, SRK-EOS, PT-EOS) combined with three mixing rules(MR-Q, MR-AS, MR-PR). An objective function of relative average deviation gave a better correlation for this high-pressure vapor equilibria of turmerones and carbon dioxide system.
URI: http://hdl.handle.net/11455/3588
其他識別: U0005-2508200613375600
Appears in Collections:化學工程學系所

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