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標題: Lipophilic C-60-derivative-induced structural changes in phospholipid layers
作者: 施明智
Jeng, U.
Lin, T.L.
Shin, K.
Hsu, C.H.
Lee, H.Y.
Wu, M.H.
Chi, Z.A.
Shih, M.C.
Chiang, L.Y.
關鍵字: lipophilic fullerenes;phospholipid layers;neutron reflection;SAXS;reflection;adsorption
Project: Physica B-Condensed Matter
期刊/報告no:: Physica B-Condensed Matter, Volume 336, Issue 1-2, Page(s) 204-210.
We have studied the interactions of a lipophilic C-60-derivative, synthesized recently for potential biomedical applications, with phospholipid monolayers and bilayers. The results of surface pressure area isotherms, atomic force microscopic images, and neutron and X-ray scattering show consistently that the lipophilic C-60 can intercalate into monolayers as well as vesicle bilayers of the phospholipids studied. In general, the lipophilic C-60 can incorporate into the lipid membranes better in the liquid crystal phase, and modify the bending and compression modulus of the host lipid membranes significantly. (C) 2003 Elsevier Science B.V. All rights reserved.
ISSN: 0921-4526
DOI: 10.1016/s0921-4526(03)00290-4
Appears in Collections:物理學系所

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