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標題: 以二維數學模型和三維數學模型模擬橢圓與球形細胞內的擴散機制
The Mathematical Two- and Three-Dimensional Model Simulating Intracellular Diffusion in Oval Cells and Spherical Cells
作者: 賴昱維
Lai, Yu-Wei
關鍵字: apparent diffusion coefficient;胞器;steric hindrance;binding effect;幾何效應;結合效應
出版社: 化學工程學系所
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Intercellular mass molecule transport plays a critical role in biological function. It is clear that the aqueous phase of the cytoplasm is crowded rather than dilute, and that the diffusion- and partitioning coefficients of macromolecules within cytoplasm are highly restricted by steric hindrance as well as binding interactions. Cytoplasmic mobility is characterized by apparent diffusion coefficient(ADC), which includes all the diffusion resistances, we developed a two-dimensional mathematical model regulating the parameterizing geometric factors to describe intracellular diffusion within muscle cells, and a three dimensional mathematical model to isolate the factors of steric hindrance and binding effect within mouse oocytes.
其他識別: U0005-1202201012300300
Appears in Collections:化學工程學系所

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