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標題: 以二維數值模型模擬細胞的擴散及調整空間立體障礙效應與結合機制
A Two-Dimensional Mathematical Model Simulating Intracellular Diffusion Quantifies Contributions of Steric Hindrance and Binding Effect
作者: 郭哲庭
Kuo, Che-Ting
關鍵字: steric hindrance;立體空間障礙;cell;binding effect;viscosity;細胞;結合效應;黏度
出版社: 化學工程學系所
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Intracellular mass transport plays as critical role in biological function, a variety of genetic diseases are related to the mal function of intracellular transport. Previous research on quantification of cytoplasmic diffusion coefficient has isolated the binding effect as one of the factor in determination of apparent diffusion coefficient. This research further isolated steric hindrance from factor such a viscosity and binding .Contribution of retarder from diffusion obstacle such as cytoskeleton and organelles are calculated and quantified. Results of the mathematical model are compared with experimental data from literature and satisfactory agreements are obtained.
其他識別: U0005-2904200900042500
Appears in Collections:化學工程學系所

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