Please use this identifier to cite or link to this item:
|標題:||Aviglycine and propargylglycine inhibit conidial germination and mycelial growth of Fusarium oxysporum f. sp luffae||作者:||Jin, J.K.
|關鍵字:||aviglycine;Fusarium oxysporum;propargylglycine;methionine biosynthesis;aspergillus-nidulans;acid;lemna||Project:||Mycopathologia||期刊/報告no：:||Mycopathologia, Volume 158, Issue 3, Page(s) 369-375.||摘要:||
Two inhibitors, aviglycine and propargylglycine, were tested for their ability to suppress methionine synthesis thus inhibit conidial germination and mycelial growth of Czapek-Dox liquid medium grown Fusarium oxysporum f. sp. luffae. Aviglycine inhibited conidial germination in the range of 0.3-7.6 muM. The linear inhibition range for mycelial growth was about 7.6-762.9 muM. Although aviglycine did not completely inhibit both conidial germination and mycelial growth, it showed significant inhibitory effect at 1.5 muM. The inhibition range for propargylglycine against conidial germination and mycelial growth were from 0.08 to 8841 muM and from 0.8 to 884.1 muM, respectively. Propargylglycine inhibited conidial germination and mycelial growth at a concentration of 8841 muM. The EC50 values of aviglycine were 1 muM for conidial growth and 122 muM for mycelial growth, and the EC50 values of propargylglycine were 47.7 muM for conidial growth and 55.6 muM for mycelial growth. Supplement of methionine released inhibition of aviglycine or propargylglycine to conidial germination. In addition, a mixture of aviglycine (1.5 muM) and propargylglycine (8841 muM) showed additive inhibitive effect than applied alone on 10 isolates. From these results, both aviglycine and propargylglycine exhibited inhibitory activity, and suggest that they can provide potential tools to design novel fungicide against fungal pathogens.
|Appears in Collections:||生命科學系所|
Show full item record
TAIR Related Article
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.