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標題: Stem cells in the lung parenchyma and prospects for lung injury therapy
作者: Yen, C.C.
Yang, S.H.
Lin, C.Y.
Chen, C.M.
關鍵字: acute lung injury;alveolar type 1 cells;alveolar type 2 cells;lung;parenchyma;lung repair;stem cell;alveolar epithelial-cells;marrow-derived cells;respiratory-distress-syndrome;induced pulmonary-emphysema;bone-marrow;gene-therapy;retinoic acid;in-vitro;precursor cells;regenerative;medicine
Project: European Journal of Clinical Investigation
期刊/報告no:: European Journal of Clinical Investigation, Volume 36, Issue 5, Page(s) 310-319.
Until recently, it was thought that only embryonic stem cells were pluripotent and that adult stem cells were restricted in their differentiative and regenerative potential to become the tissues in which they reside. However, the discovery that adult stem cells in one tissue can contribute to the formation of other tissues, especially after injury or cell damage, implies that stem cells have developmental plasticity. For example, haematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs) from bone marrow can be used to regenerate diverse tissues at distant sites, including the lung. This article reviews the character of stem cells in the lung parenchyma and focuses on the potential uses of adult stem cells in research of lung injury and lung disease therapies.
ISSN: 0014-2972
DOI: 10.1111/j.1365-2362.2006.01638.x
Appears in Collections:生命科學系所

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