Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/38593
標題: Unusual roles of host metabolic enzymes and housekeeping proteins in plant virus replication
作者: Huang, Ying-Wen
Hu, Chung-Chi
Lin, Na-Sheng
Hsu, Yau-Heiu
Project: Current Opinion in virology, Volume 2, Issue 6, Page(s) 676–682.
摘要: 
Viruses have developed the ability to improvise their own
replication machineries with host proteins, adapt to different
environments, and overcome difficulties encountered during
various stages of their infection cycles. The modular nature of
protein functional motifs allows for the novel use of ordinary
host factors. Recent studies have revealed that positive-sense
RNA [(+)RNA] viruses may adapt regular metabolic enzymes
and housekeeping proteins of host plants by exploiting unusual
functions to accommodate their need for replication, mainly for
recruitment and subcellular localization of RNA templates or
components of replicase complexes and for controlling
switches in different stages of replication. This review
compares the newly discovered roles of selected metabolic
enzymes and housekeeping proteins in plant (+)RNA virus
replication with their original cellular functions and the different
consequences when utilized by different viruses.
URI: http://hdl.handle.net/11455/38593
ISSN: 1879-6257
DOI: 10.1016/j.coviro.2012.10.002
Appears in Collections:生命科學系所

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