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Influence of Mixing Efficiency in Microchannels by Pulsing Flows
|關鍵字:||微混合器;Micromixer;微流體;數值模擬;Microfluidic;Numerical simulation||出版社:||生醫工程研究所||引用:|| A. Manz, N. Graber, and H. M. Widmer, "Miniaturized total chemical analysis systems: a novel concept for chemical sensing," Sensors and Actuators B: Chemical, vol. 1, pp. 244-248, 1990.  F. M. White, Viscous fluid flow vol. 2: McGraw-Hill New York, 1991.  A. A. Deshmukh, D. Liepmann, and A. P. Pisano, "Continuous micromixer with pulsatile micropumps," 2000, pp. 73-76.  X. N. a. Y.-K. Lee, "Efficient spatial-temporal chaotic mixing in microchannels," Journal of micromechanics and microengineering, pp. 454–462, 2003.  H. Suzuki and C. M. Ho, "A magnetic force driven chaotic micro-mixer," 2002, pp. 40-43.  K. S. R. Liang-Hsuan Lu, and Chang Liu, "A magnetic microstirrer and array for microfluidic mixing," Journal of Microelectromechanical Systems, vol. 11 , Issue: 5 pp. 462 - 469 2002.  A. O. El Moctar, N. Aubry, and J. Batton, "Electro-hydrodynamic micro-fluidic mixer," Lab Chip, vol. 3, pp. 273-280, 2003.  J. Deval, P. Tabeling, and C. M. Ho, "A dielectrophoretic chaotic mixer," 2002, pp. 36-39.  Z. Yang, S. Matsumoto, H. Goto, M. Matsumoto, and R. Maeda, "Ultrasonic micromixer for microfluidic systems," Sensors and Actuators A: Physical, vol. 93, pp. 266-272, 2001.  K. Yasuda, "Non-destructive, non-contact handling method for biomaterials in micro-chamber by ultrasound," Sensors and Actuators B: Chemical, vol. 64, pp. 128-135, 2000.  D. Gobby, P. Angeli, and A. Gavriilidis, "Mixing characteristics of T-type microfluidic mixers," Journal of micromechanics and microengineering, vol. 11, p. 126, 2001.  Y. Z. Liu, B. J. Kim, and H. J. Sung, "Two-fluid mixing in a microchannel," International journal of heat and fluid flow, vol. 25, pp. 986-995, 2004.  A. D. Stroock, S. K. W. Dertinger, A. Ajdari, I. Mezić, H. A. Stone, and G. M. Whitesides, "Chaotic mixer for microchannels," Science, vol. 295, p. 647, 2002.  L. Wang and J. T. Yang, "An overlapping crisscross micromixer using chaotic mixing principles," Journal of micromechanics and microengineering, vol. 16, p. 2684, 2006.  S. Lee, H. Lee, I. Lee, and C. Tseng, "Ink diffusion in water," European journal of physics, vol. 25, p. 331, 2004.  C. H. Lin, L. M. Fu, and Y. S. Chien, "Microfluidic T-form mixer utilizing switching electroosmotic flow," Analytical chemistry, vol. 76, pp. 5265-5272, 2004.  M.-H. H. Wei-Feng Fang, Yu-Tzu Chen, and Jing-Tang Yang, "Characterization of microfluidic mixing and reaction in microchannels via analysis of cross-sectional patterns," Journal List Biomicrofluidics, 2011.||摘要:||
The major objective of the present study is to explore the two-fluid mixing enhancement by the pulsing flows in T-type mixer with numerical and experimental methods. The inflows to the mixer were constant flow with a fixed flow rate or periodic pulses with phase shift from both of T-type mixer inlets. The research results indicate that there is a clear trend for higher mixing efficiency with increasing distance and decreasing flow rate. The phase shift and frequency of pulses did not improve mixing; however, the mixing efficiency is highly dependent on flow rate and different pulsing wave. The best mixing condition is a triangle pulsing wave with out-of- phase and 0.5 Hz.
A computational fluid dynamic package FLUENT was used to simulate the flow field. The simulated flow field and the calculated mixing efficiency of the microchannel mixers were compared with those obtained from experiments. The results show that the results by experiment and numerical simulation are consistent in the cases of fixed flow rates (no pulsing) and square wave pulsing. The experimental mixing efficiencies of triangle wave and the accelerating right triangle wave were higher than that of the simulation; on the other hand, the experimental mixing efficiency of the decelerating right triangle wave was lower than that of the simulation.
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