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標題: 三重推動力新型分離晶片平台
Triplex-Pumping CD-Like Microfludic Platform with Parabolic Microchannels
作者: 張峻豪
關鍵字: 生物晶片;分離;BSA
出版社: 精密工程研究所

Centrifugal force and electric field force are the commonly used driving gear for electrophoresis based biomedical separation systems. The centrifugal force is implemented in the CD-like diagnostic systems; while the electric field force is mainly adopted in the chip-based capillary electrophoresis systems. Due to the ability to process multi-reactions simultaneously, the centrifugal force driving CD-like diagnostic platform is gaining more attentions from both the academia and the industrial community.
In this research, we propose a novel CD-like multi-channel electrophoresis based biomedical separation system that is driven by the interactions of the centrifugal force, the electric field force, and the Coriolis force. In this novel platform, heat-conduction theory is implemented to formulate the relations between the sample velocity and the dimension of the microchannel. The parabola microchannel that has the least friction force under triplex-pumping forces is determined by computer simulations. The centrifugal force control of this system is realized through the velocity control of a DC servo motor, while the electric field is governed through multi-stage potential circuits, which are suitably designed and fabricated by sputtering on metal mask method, can be adjusted to provide multi-stage voltages.
Appears in Collections:精密工程研究所

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