Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/40338
DC FieldValueLanguage
dc.contributor.authorYu, S.L.en_US
dc.contributor.author陳健尉zh_TW
dc.contributor.authorChen, H.Y.en_US
dc.contributor.authorYang, P.C.en_US
dc.contributor.authorChen, J.J.W.en_US
dc.date2007zh_TW
dc.date.accessioned2014-06-06T08:03:37Z-
dc.date.available2014-06-06T08:03:37Z-
dc.identifier.issn1044-5498zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/40338-
dc.description.abstractMicroRNAs (miRNAs) are endogenous small non-protein-coding RNAs (18-25 nucleotides) that conduct the post-transcriptional repression of hundreds of their target proteins. They regulate many kinds of basic cellular processes including proliferation, differentiation, stress response, and cell death. Recent evidence has shown that deregulation of miRNAs correlates with certain features of diverse cancers ( such as tumorigenesis, differentiation status, and outcome of tumor patients), and indicates that miRNAs can act as oncogenes or tumor suppressors. Here, we summarize these recent studies and provide a new perspective on understanding the role of miRNAs in initiation and progression of cancers. We also discuss the future applications of miRNAs in diagnostic and prognostic implications of cancers.en_US
dc.language.isoen_USzh_TW
dc.relationDNA and Cell Biologyen_US
dc.relation.ispartofseriesDNA and Cell Biology, Volume 26, Issue 5, Page(s) 283-292.en_US
dc.relation.urihttp://dx.doi.org/10.1089/dna.2006.0555en_US
dc.subjectangiotensin-ii type-1en_US
dc.subjectcell lung-canceren_US
dc.subjectchronic lymphocytic-leukemiaen_US
dc.subjectdown-regulationen_US
dc.subjectbreast-canceren_US
dc.subjectc-mycen_US
dc.subjectexpressionen_US
dc.subjectgeneen_US
dc.subjectrnaen_US
dc.subjecttargetsen_US
dc.titleUnique microRNA signature and clinical outcome of cancersen_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1089/dna.2006.0555zh_TW
item.cerifentitytypePublications-
item.grantfulltextnone-
item.languageiso639-1en_US-
item.fulltextno fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeJournal Article-
Appears in Collections:生物醫學研究所
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