Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/41025
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dc.contributor.authorZang, Chi-Zongen_US
dc.contributor.authorChang, Yaw-Nanen_US
dc.contributor.authorChen, Hua-Bingen_US
dc.contributor.authorWu, Jiun-Yanen_US
dc.contributor.authorChen, Chih-Ien_US
dc.contributor.authorHuang, Jenn-Wenen_US
dc.contributor.authorShih, Hsin-Deren_US
dc.contributor.authorLiu, Yung-Chuanen_US
dc.contributor.other國立中興大學化學工程學系zh_TW
dc.contributor.otherNational Chung Hsing University,Department of Chemical Engineeringen_US
dc.date2011-5zh_TW
dc.date.accessioned2014-06-06T08:04:50Z-
dc.date.available2014-06-06T08:04:50Z-
dc.identifier.issn1876-1070zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/41025-
dc.description.abstractFungichromin (FC), a polyene macrolide antibiotic, was found to be useful in the treatment of resistance for plant diseases such as Rhizoctonia damping-off of cabbage and tomato late blight. A novel strain, Streptomyces padanus PMS-702, was employed to study the cultivation conditions for FC production. When using linoleic acid as an additive, a negative effect on FC production was observed. On the contrary, when using oleic acid in concentration of 0.01 M (2.82 g/L), a 3.5-fold enhancement of FC production with a slight increase in cell biomass was obtained. To study the effects of plant oils, various plant oils were used as additives. It was found that all the plant oils (namely, corn oil, olive oil and etc.) promote FC production up to about 4.9-fold as compared to that without such an addition. A quantitative analysis on FC yield indicated that, at a lower concentration, fatty acids and plant oils play roles as both a stimulator and a carbon source whereas, at a higher concentration, they serve mainly as the carbon source. This morphological study showed that the addition of fatty acids and oils in the medium vary the cell membrane permeability. The fact that FC could be rapidly secreted out into the medium after its synthesis as well as its stimulatory effect attributed to a dramatic increase in FC production.en_US
dc.language.isoen_USzh_TW
dc.publisherElsevier B.V.en_US
dc.relationJournal of the Taiwan Institute of Chemical Engineers, Volume 42, Issue 3, Page(s) 413-418.en_US
dc.subjectStreptomyces padanus PMS-702en_US
dc.subjectFermentationen_US
dc.subjectFungichrominen_US
dc.subjectPolyene macrolide antibioticen_US
dc.subjectFatty acid additionen_US
dc.subjectOil additionen_US
dc.subjectCell morphologyen_US
dc.titleDeciphering the roles of fatty acids and oils in fungichromin enhancement from Streptomyces padanusen_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1016/j.jtice.2010.09.010zh_TW
dc.contributor.catalogerMiao-zhen Luoen_US
item.grantfulltextnone-
item.fulltextno fulltext-
item.cerifentitytypePublications-
item.languageiso639-1en_US-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeJournal Article-
Appears in Collections:化學工程學系所
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