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標題: Interactions between nonionic Triton X surfactants and cholesterol-containing phosphatidylcholine liposomes
作者: Chern, C.S.
Chiu, H.C.
Yang, Y.S.
關鍵字: liposome;nonionic surfactants;structural transformation of vesicles;solubilization kinetics experiments;liposome stability ratio;sodium dodecyl-sulfate;vesicle transition;lecithin vesicles;ionic;surfactants;octyl glucoside;solubilization;mechanism;detergents;bilayers;protein
Project: Journal of Colloid and Interface Science
期刊/報告no:: Journal of Colloid and Interface Science, Volume 302, Issue 1, Page(s) 335-340.
Solubilization kinetics experiments were developed to study the effects of the polyethylene glycol chain length of Triton X surfactants on their interactions with the cholesterol-containing phosphatidylcholine vesicles. An empirical liposome stability ratio was used to describe the vesicle solubilization process. The effectiveness of Triton X surfactants in solubilizing vesicles decreases with increasing polyethylene glycol chain length of surfactants. It was also shown that vesicles containing the intercalated surfactant molecules with the largest number of ethylene glycol units per molecule exhibited the exceedingly retarded solubilization behavior. Independent experiments based on a thermodynamic approach provide supporting evidence for the conclusions obtained from solubilization kinetics experiments. (c) 2006 Elsevier Inc. All rights reserved.
ISSN: 0021-9797
DOI: 10.1016/j.jcis.2006.06.028
Appears in Collections:化學工程學系所

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